Correction to: Direct effects of doxorubicin on skeletal muscle contribute to fatigue

K. van Norren; A. van Helvoort; J.M. Agriles; S. van Tuijl; K. Arts; M. Gorselink; A. Laviano; D. Kegler; H.P. Haagsman; E.M. van der Beek

doi:10.1038/sj.bjc.6604992

Correction to: Direct effects of doxorubicin on skeletal muscle contribute to fatigue

K. van Norren, A. van Helvoort, J.M. Agriles, S. van Tuijl, K. Arts, M. Gorselink, A. Laviano, D. Kegler, H.P. Haagsman, E.M. van der Beek

Research output: Contribution to journal › Comment/Letter to the editor › Academic

Abstract

Chemotherapy-induced fatigue is a multidimensional symptom. Oxidative stress has been proposed as a working mechanism for anthracycline-induced cardiotoxicity. In this study, doxorubicin (DOX) was tested on skeletal muscle function. Doxorubicin induced impaired ex vivo skeletal muscle relaxation followed in time by contraction impediment, which could be explained by DOX-induced changes in Ca(2+) responses of myotubes in vitro. The Ca(2+) responses in skeletal muscle, however, could not be explained by oxidative stress

Original language	English
Pages (from-to)	1014-1014
Journal	British Journal of Cancer
Volume	100
Issue number	2
DOIs	https://doi.org/10.1038/sj.bjc.6604992
Publication status	Published - 2009

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title = "Correction to: Direct effects of doxorubicin on skeletal muscle contribute to fatigue",

abstract = "Chemotherapy-induced fatigue is a multidimensional symptom. Oxidative stress has been proposed as a working mechanism for anthracycline-induced cardiotoxicity. In this study, doxorubicin (DOX) was tested on skeletal muscle function. Doxorubicin induced impaired ex vivo skeletal muscle relaxation followed in time by contraction impediment, which could be explained by DOX-induced changes in Ca(2+) responses of myotubes in vitro. The Ca(2+) responses in skeletal muscle, however, could not be explained by oxidative stress",

author = "{van Norren}, K. and {van Helvoort}, A. and J.M. Agriles and {van Tuijl}, S. and K. Arts and M. Gorselink and A. Laviano and D. Kegler and H.P. Haagsman and {van der Beek}, E.M.",

year = "2009",

doi = "10.1038/sj.bjc.6604992",

language = "English",

volume = "100",

pages = "1014--1014",

journal = "British Journal of Cancer",

issn = "0007-0920",

publisher = "Cancer Research UK",

number = "2",

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TY - JOUR

T1 - Correction to: Direct effects of doxorubicin on skeletal muscle contribute to fatigue

AU - van Norren, K.

AU - van Helvoort, A.

AU - Agriles, J.M.

AU - van Tuijl, S.

AU - Arts, K.

AU - Gorselink, M.

AU - Laviano, A.

AU - Kegler, D.

AU - Haagsman, H.P.

AU - van der Beek, E.M.

PY - 2009

Y1 - 2009

N2 - Chemotherapy-induced fatigue is a multidimensional symptom. Oxidative stress has been proposed as a working mechanism for anthracycline-induced cardiotoxicity. In this study, doxorubicin (DOX) was tested on skeletal muscle function. Doxorubicin induced impaired ex vivo skeletal muscle relaxation followed in time by contraction impediment, which could be explained by DOX-induced changes in Ca(2+) responses of myotubes in vitro. The Ca(2+) responses in skeletal muscle, however, could not be explained by oxidative stress

AB - Chemotherapy-induced fatigue is a multidimensional symptom. Oxidative stress has been proposed as a working mechanism for anthracycline-induced cardiotoxicity. In this study, doxorubicin (DOX) was tested on skeletal muscle function. Doxorubicin induced impaired ex vivo skeletal muscle relaxation followed in time by contraction impediment, which could be explained by DOX-induced changes in Ca(2+) responses of myotubes in vitro. The Ca(2+) responses in skeletal muscle, however, could not be explained by oxidative stress

U2 - 10.1038/sj.bjc.6604992

DO - 10.1038/sj.bjc.6604992

M3 - Comment/Letter to the editor

SN - 0007-0920

VL - 100

SP - 1014

EP - 1014

JO - British Journal of Cancer

JF - British Journal of Cancer

IS - 2

ER -

Correction to: Direct effects of doxorubicin on skeletal muscle contribute to fatigue

Abstract

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