Correcting palindromes in long reads after whole-genome amplification

S. Warris^*, E.G.W.M. Schijlen, H.C. van de Geest, R. Vegesna, T. Hesselink, B. te Lintel Hekkert, G.F. Sanchez Perez, P. Medvedev, K.D. Makova, D. de Ridder

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Whole-genome amplification (WGA) create specific chimeric fragments, which consist mainly of palindrome sequences. We developed the tool Pacasus to detect and correct these palindromic sequences in long reads, for example from PacBio and Nanopore
Warris, S. (Creator), Schijlen, E. G. W. M. (Creator), van de Geest, H. C. (Creator), Vegesna, R. (Creator), Hesselink, T. (Creator), te Lintel Hekkert, B. (Creator), Sanchez Perez, G. F. (Creator), Medvedev, P. (Creator), Makova, K. D. (Creator) & de Ridder, D. (Creator), Wageningen UR, 31 Jul 2017
https://www.ebi.ac.uk/ena/data/view/PRJEB21791
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