Core and corona structure of mixed polymeric micelles

I.K. Voets; A. de Keizer; M.A. Cohen Stuart; P. de Waard

doi:10.1021/ma060965o

Core and corona structure of mixed polymeric micelles

I.K. Voets, A. de Keizer, M.A. Cohen Stuart, P. de Waard

Biophysics

Research output: Contribution to journal › Article › Academic › peer-review

53 Citations (Scopus)

Abstract

Mixed polymeric micelles have been prepared from aqueous solutions of poly(2-(dimethylamino)ethyl methacrylate)-block-poly(glyceryl methacrylate), PDMAEMA45-b-PGMA90, and poly(acrylic acid)-block-poly(acrylamide), PAA42-b-PAAm417, through complex coacervation of the oppositely charged blocks. Rather monodisperse, spherical aggregates are formed with a Rh = 15.2 ± 0.4 nm. The extent of chain mixing between poly(acrylic acid) and poly(2-(dimethylamino)ethyl methacrylate) in the micellar core and poly(acrylamide) and poly(glyceryl methacrylate) in the micellar corona has been investigated by 2D 1H NMR NOESY experiments. The presence of cross-peaks for protons in different core and corona blocks indicates that the two blocks are in close proximity (

Original language	English
Pages (from-to)	5952-5955
Journal	Macromolecules
Volume	39
Issue number	7
DOIs	https://doi.org/10.1021/ma060965o
Publication status	Published - 2006

Keywords

abc triblock copolymers
multicompartment micelles
integral-equations
block-copolymers
janus micelles
aqueous-media
vesicles
water
terpolymer
chains

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10.1021/ma060965o

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title = "Core and corona structure of mixed polymeric micelles",

abstract = "Mixed polymeric micelles have been prepared from aqueous solutions of poly(2-(dimethylamino)ethyl methacrylate)-block-poly(glyceryl methacrylate), PDMAEMA45-b-PGMA90, and poly(acrylic acid)-block-poly(acrylamide), PAA42-b-PAAm417, through complex coacervation of the oppositely charged blocks. Rather monodisperse, spherical aggregates are formed with a Rh = 15.2 ± 0.4 nm. The extent of chain mixing between poly(acrylic acid) and poly(2-(dimethylamino)ethyl methacrylate) in the micellar core and poly(acrylamide) and poly(glyceryl methacrylate) in the micellar corona has been investigated by 2D 1H NMR NOESY experiments. The presence of cross-peaks for protons in different core and corona blocks indicates that the two blocks are in close proximity (",

keywords = "abc triblock copolymers, multicompartment micelles, integral-equations, block-copolymers, janus micelles, aqueous-media, vesicles, water, terpolymer, chains",

author = "I.K. Voets and \{de Keizer\}, A. and \{Cohen Stuart\}, M.A. and \{de Waard\}, P.",

year = "2006",

doi = "10.1021/ma060965o",

language = "English",

volume = "39",

pages = "5952--5955",

journal = "Macromolecules",

issn = "0024-9297",

publisher = "American Chemical Society (ACS)",

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TY - JOUR

T1 - Core and corona structure of mixed polymeric micelles

AU - Voets, I.K.

AU - de Keizer, A.

AU - Cohen Stuart, M.A.

AU - de Waard, P.

PY - 2006

Y1 - 2006

N2 - Mixed polymeric micelles have been prepared from aqueous solutions of poly(2-(dimethylamino)ethyl methacrylate)-block-poly(glyceryl methacrylate), PDMAEMA45-b-PGMA90, and poly(acrylic acid)-block-poly(acrylamide), PAA42-b-PAAm417, through complex coacervation of the oppositely charged blocks. Rather monodisperse, spherical aggregates are formed with a Rh = 15.2 ± 0.4 nm. The extent of chain mixing between poly(acrylic acid) and poly(2-(dimethylamino)ethyl methacrylate) in the micellar core and poly(acrylamide) and poly(glyceryl methacrylate) in the micellar corona has been investigated by 2D 1H NMR NOESY experiments. The presence of cross-peaks for protons in different core and corona blocks indicates that the two blocks are in close proximity (

AB - Mixed polymeric micelles have been prepared from aqueous solutions of poly(2-(dimethylamino)ethyl methacrylate)-block-poly(glyceryl methacrylate), PDMAEMA45-b-PGMA90, and poly(acrylic acid)-block-poly(acrylamide), PAA42-b-PAAm417, through complex coacervation of the oppositely charged blocks. Rather monodisperse, spherical aggregates are formed with a Rh = 15.2 ± 0.4 nm. The extent of chain mixing between poly(acrylic acid) and poly(2-(dimethylamino)ethyl methacrylate) in the micellar core and poly(acrylamide) and poly(glyceryl methacrylate) in the micellar corona has been investigated by 2D 1H NMR NOESY experiments. The presence of cross-peaks for protons in different core and corona blocks indicates that the two blocks are in close proximity (

KW - abc triblock copolymers

KW - multicompartment micelles

KW - integral-equations

KW - block-copolymers

KW - janus micelles

KW - aqueous-media

KW - vesicles

KW - water

KW - terpolymer

KW - chains

U2 - 10.1021/ma060965o

DO - 10.1021/ma060965o

M3 - Article

SN - 0024-9297

VL - 39

SP - 5952

EP - 5955

JO - Macromolecules

JF - Macromolecules

IS - 7

ER -

Core and corona structure of mixed polymeric micelles

Abstract

Keywords

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