Convergent evolution for antibiotic biosynthesis in bacteria and animals

Nicolas Papon; Vincent Courdavault; Marnix H. Medema

doi:10.1016/j.tig.2023.02.005

Convergent evolution for antibiotic biosynthesis in bacteria and animals

Nicolas Papon^*, Vincent Courdavault^*, Marnix H. Medema^*

^*Corresponding author for this work

Bioinformatics (BIF)

Research output: Contribution to journal › Short survey › peer-review

Abstract

Convergent evolution has been described for several metabolic pathways across the kingdoms of life. However, there is hitherto no evidence for such an interkingdom process for antimicrobials. A new report suggests that marine animals have evolved the ability to biosynthesize antimicrobial polyketides, in parallel with bacteria.

Original language	English
Pages (from-to)	237-239
Journal	Trends in Genetics
Volume	39
Issue number	4
Early online date	21 Feb 2023
DOIs	https://doi.org/10.1016/j.tig.2023.02.005
Publication status	Published - Apr 2023

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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https://edepot.wur.nl/591057Licence: Taverne

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title = "Convergent evolution for antibiotic biosynthesis in bacteria and animals",

abstract = "Convergent evolution has been described for several metabolic pathways across the kingdoms of life. However, there is hitherto no evidence for such an interkingdom process for antimicrobials. A new report suggests that marine animals have evolved the ability to biosynthesize antimicrobial polyketides, in parallel with bacteria.",

author = "Nicolas Papon and Vincent Courdavault and Medema, {Marnix H.}",

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AU - Papon, Nicolas

AU - Courdavault, Vincent

AU - Medema, Marnix H.

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N2 - Convergent evolution has been described for several metabolic pathways across the kingdoms of life. However, there is hitherto no evidence for such an interkingdom process for antimicrobials. A new report suggests that marine animals have evolved the ability to biosynthesize antimicrobial polyketides, in parallel with bacteria.

AB - Convergent evolution has been described for several metabolic pathways across the kingdoms of life. However, there is hitherto no evidence for such an interkingdom process for antimicrobials. A new report suggests that marine animals have evolved the ability to biosynthesize antimicrobial polyketides, in parallel with bacteria.

U2 - 10.1016/j.tig.2023.02.005

DO - 10.1016/j.tig.2023.02.005

M3 - Short survey

C2 - 36822964

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JO - Trends in Genetics

JF - Trends in Genetics

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ER -

Convergent evolution for antibiotic biosynthesis in bacteria and animals

Abstract

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