Convalescent pigs are protected completely against infection with a homologous Actinobacillus pleuropneumoniae strain but incompletely against a heterologous-serotype strain

A.L.M. Cruijsen, L.A.M.G. van Leengoed, M. Ham-Hoffjes, J.H.M. Verheijden

    Research output: Contribution to journalArticleAcademicpeer-review

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    Abstract

    To study whether Actinobacillus pleuropneumoniae induces a species- specific immunity, we infected pigs in the left lung with serotype 3 or 9 and after 3 weeks we infected their right lungs with serotype 9. Convalescent pigs were protected against homologous strain reinfection, but after heterologous strain reinfection the degree of protection varied. Neutralizing antibodies were not essential for protection.
    Original languageEnglish
    Pages (from-to)2341-2343
    JournalInfection and Immunity
    Volume63
    Issue number6
    Publication statusPublished - 1995

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    Actinobacillus pleuropneumoniae
    Swine
    Lung
    Infection
    Neutralizing Antibodies
    Immunity
    Serogroup

    Cite this

    @article{80872d716b4447ed8a4ca6e4a707cd03,
    title = "Convalescent pigs are protected completely against infection with a homologous Actinobacillus pleuropneumoniae strain but incompletely against a heterologous-serotype strain",
    abstract = "To study whether Actinobacillus pleuropneumoniae induces a species- specific immunity, we infected pigs in the left lung with serotype 3 or 9 and after 3 weeks we infected their right lungs with serotype 9. Convalescent pigs were protected against homologous strain reinfection, but after heterologous strain reinfection the degree of protection varied. Neutralizing antibodies were not essential for protection.",
    author = "A.L.M. Cruijsen and {van Leengoed}, L.A.M.G. and M. Ham-Hoffjes and J.H.M. Verheijden",
    year = "1995",
    language = "English",
    volume = "63",
    pages = "2341--2343",
    journal = "Infection and Immunity",
    issn = "0019-9567",
    publisher = "American Society for Microbiology",
    number = "6",

    }

    Convalescent pigs are protected completely against infection with a homologous Actinobacillus pleuropneumoniae strain but incompletely against a heterologous-serotype strain. / Cruijsen, A.L.M.; van Leengoed, L.A.M.G.; Ham-Hoffjes, M.; Verheijden, J.H.M.

    In: Infection and Immunity, Vol. 63, No. 6, 1995, p. 2341-2343.

    Research output: Contribution to journalArticleAcademicpeer-review

    TY - JOUR

    T1 - Convalescent pigs are protected completely against infection with a homologous Actinobacillus pleuropneumoniae strain but incompletely against a heterologous-serotype strain

    AU - Cruijsen, A.L.M.

    AU - van Leengoed, L.A.M.G.

    AU - Ham-Hoffjes, M.

    AU - Verheijden, J.H.M.

    PY - 1995

    Y1 - 1995

    N2 - To study whether Actinobacillus pleuropneumoniae induces a species- specific immunity, we infected pigs in the left lung with serotype 3 or 9 and after 3 weeks we infected their right lungs with serotype 9. Convalescent pigs were protected against homologous strain reinfection, but after heterologous strain reinfection the degree of protection varied. Neutralizing antibodies were not essential for protection.

    AB - To study whether Actinobacillus pleuropneumoniae induces a species- specific immunity, we infected pigs in the left lung with serotype 3 or 9 and after 3 weeks we infected their right lungs with serotype 9. Convalescent pigs were protected against homologous strain reinfection, but after heterologous strain reinfection the degree of protection varied. Neutralizing antibodies were not essential for protection.

    M3 - Article

    VL - 63

    SP - 2341

    EP - 2343

    JO - Infection and Immunity

    JF - Infection and Immunity

    SN - 0019-9567

    IS - 6

    ER -