Convalescent pigs are protected completely against infection with a homologous Actinobacillus pleuropneumoniae strain but incompletely against a heterologous-serotype strain

A.L.M. Cruijsen; L.A.M.G. van Leengoed; M. Ham-Hoffjes; J.H.M. Verheijden

Convalescent pigs are protected completely against infection with a homologous Actinobacillus pleuropneumoniae strain but incompletely against a heterologous-serotype strain

A.L.M. Cruijsen, L.A.M.G. van Leengoed, M. Ham-Hoffjes, J.H.M. Verheijden

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

To study whether Actinobacillus pleuropneumoniae induces a species- specific immunity, we infected pigs in the left lung with serotype 3 or 9 and after 3 weeks we infected their right lungs with serotype 9. Convalescent pigs were protected against homologous strain reinfection, but after heterologous strain reinfection the degree of protection varied. Neutralizing antibodies were not essential for protection.

Original language	English
Pages (from-to)	2341-2343
Journal	Infection and Immunity
Volume	63
Issue number	6
Publication status	Published - 1995

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@article{80872d716b4447ed8a4ca6e4a707cd03,

title = "Convalescent pigs are protected completely against infection with a homologous Actinobacillus pleuropneumoniae strain but incompletely against a heterologous-serotype strain",

abstract = "To study whether Actinobacillus pleuropneumoniae induces a species- specific immunity, we infected pigs in the left lung with serotype 3 or 9 and after 3 weeks we infected their right lungs with serotype 9. Convalescent pigs were protected against homologous strain reinfection, but after heterologous strain reinfection the degree of protection varied. Neutralizing antibodies were not essential for protection.",

author = "A.L.M. Cruijsen and {van Leengoed}, L.A.M.G. and M. Ham-Hoffjes and J.H.M. Verheijden",

year = "1995",

language = "English",

volume = "63",

pages = "2341--2343",

journal = "Infection and Immunity",

issn = "0019-9567",

publisher = "American Society for Microbiology",

number = "6",

}

Convalescent pigs are protected completely against infection with a homologous Actinobacillus pleuropneumoniae strain but incompletely against a heterologous-serotype strain. / Cruijsen, A.L.M.; van Leengoed, L.A.M.G.; Ham-Hoffjes, M.; Verheijden, J.H.M.

In: Infection and Immunity, Vol. 63, No. 6, 1995, p. 2341-2343.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Convalescent pigs are protected completely against infection with a homologous Actinobacillus pleuropneumoniae strain but incompletely against a heterologous-serotype strain

AU - Cruijsen, A.L.M.

AU - van Leengoed, L.A.M.G.

AU - Ham-Hoffjes, M.

AU - Verheijden, J.H.M.

PY - 1995

Y1 - 1995

N2 - To study whether Actinobacillus pleuropneumoniae induces a species- specific immunity, we infected pigs in the left lung with serotype 3 or 9 and after 3 weeks we infected their right lungs with serotype 9. Convalescent pigs were protected against homologous strain reinfection, but after heterologous strain reinfection the degree of protection varied. Neutralizing antibodies were not essential for protection.

AB - To study whether Actinobacillus pleuropneumoniae induces a species- specific immunity, we infected pigs in the left lung with serotype 3 or 9 and after 3 weeks we infected their right lungs with serotype 9. Convalescent pigs were protected against homologous strain reinfection, but after heterologous strain reinfection the degree of protection varied. Neutralizing antibodies were not essential for protection.

M3 - Article

VL - 63

SP - 2341

EP - 2343

JO - Infection and Immunity

JF - Infection and Immunity

SN - 0019-9567

IS - 6

ER -

Convalescent pigs are protected completely against infection with a homologous Actinobacillus pleuropneumoniae strain but incompletely against a heterologous-serotype strain

Abstract

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