Consumption of antimicrobials in pigs, veal calves, and broilers in the Netherlands: Quantitative results of nationwide collection of data in 2011

M.E.H. Bos, F.J. Taverne, I.M. van Geijlswijk, J.W. Mouton, D.J. Mevius, D.J.J. Heederik

Research output: Contribution to journalArticleAcademicpeer-review

53 Citations (Scopus)

Abstract

In 2011, Dutch animal production sectors started recording veterinary antimicrobial consumption. These data are used by the Netherlands Veterinary Medicines Authority to create transparency in and define benchmark indicators for veterinary consumption of antimicrobials. This paper presents the results of sector wide consumption of antimicrobials, in the form of prescriptions or deliveries, for all pig, veal calf, and broiler farms. Data were used to calculate animal defined daily dosages per year (ADDD/Y) per pig or veal calf farm. For broiler farms, number of animal treatment days per year was calculated. Furthermore, data were used to calculate the consumption of specific antimicrobial classes per administration route per pig or veal calf farm. The distribution of antimicrobial consumption per farm varied greatly within and between farm categories. All categories, except for rosé starter farms, showed a highly right skewed distribution with a long tail. Median ADDD/Y values varied from 1.2 ADDD/Y for rosé finisher farms to 83.2 ADDD/Y for rosé starter farms, with 28.6 ADDD/Y for white veal calf farms. Median consumption in pig farms was 9.3 ADDD/Y for production pig farms and 3.0 ADDD/Y for slaughter pig farms. Median consumption in broiler farms was 20.9 ATD/Y. Regarding specific antimicrobial classes, fluoroquinolones were mainly used on veal calf farms, but in low quantities: P75 range was 0 – 0.99 ADDD/Y, and 0 – 0.04 ADDD/Y in pig farms. The P75 range for 3rd/4th-generation cephalosporins was 0 – 0.07 ADDD/Y for veal calf farms, and 0 – 0.1 ADDD/Y for pig farms. The insights obtained from these results, and the full transparency obtained by monitoring antimicrobial consumption per farm, will help reduce antimicrobial consumption and endorse antimicrobial stewardship. The wide and skewed distribution in consumption has important practical and methodological implications for benchmarking, surveillance and future analysis of trends.
Original languageEnglish
Article numbere77525
Number of pages9
JournalPLoS ONE
Volume8
Issue number10
DOIs
Publication statusPublished - 2013

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veal calves
Netherlands
Farms
Swine
anti-infective agents
broiler chickens
farms
swine
Animals
dosage
animals
Benchmarking
Domestic Animals
Starters
Transparency
Veterinary medicine
farm numbers
Veterinary Medicine
cephalosporins
fluoroquinolones

Keywords

  • resistant staphylococcus-aureus
  • escherichia-coli
  • animals
  • farmers
  • health
  • costs
  • herds
  • usage
  • meat
  • food

Cite this

Bos, M.E.H. ; Taverne, F.J. ; van Geijlswijk, I.M. ; Mouton, J.W. ; Mevius, D.J. ; Heederik, D.J.J. / Consumption of antimicrobials in pigs, veal calves, and broilers in the Netherlands: Quantitative results of nationwide collection of data in 2011. In: PLoS ONE. 2013 ; Vol. 8, No. 10.
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abstract = "In 2011, Dutch animal production sectors started recording veterinary antimicrobial consumption. These data are used by the Netherlands Veterinary Medicines Authority to create transparency in and define benchmark indicators for veterinary consumption of antimicrobials. This paper presents the results of sector wide consumption of antimicrobials, in the form of prescriptions or deliveries, for all pig, veal calf, and broiler farms. Data were used to calculate animal defined daily dosages per year (ADDD/Y) per pig or veal calf farm. For broiler farms, number of animal treatment days per year was calculated. Furthermore, data were used to calculate the consumption of specific antimicrobial classes per administration route per pig or veal calf farm. The distribution of antimicrobial consumption per farm varied greatly within and between farm categories. All categories, except for ros{\'e} starter farms, showed a highly right skewed distribution with a long tail. Median ADDD/Y values varied from 1.2 ADDD/Y for ros{\'e} finisher farms to 83.2 ADDD/Y for ros{\'e} starter farms, with 28.6 ADDD/Y for white veal calf farms. Median consumption in pig farms was 9.3 ADDD/Y for production pig farms and 3.0 ADDD/Y for slaughter pig farms. Median consumption in broiler farms was 20.9 ATD/Y. Regarding specific antimicrobial classes, fluoroquinolones were mainly used on veal calf farms, but in low quantities: P75 range was 0 – 0.99 ADDD/Y, and 0 – 0.04 ADDD/Y in pig farms. The P75 range for 3rd/4th-generation cephalosporins was 0 – 0.07 ADDD/Y for veal calf farms, and 0 – 0.1 ADDD/Y for pig farms. The insights obtained from these results, and the full transparency obtained by monitoring antimicrobial consumption per farm, will help reduce antimicrobial consumption and endorse antimicrobial stewardship. The wide and skewed distribution in consumption has important practical and methodological implications for benchmarking, surveillance and future analysis of trends.",
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Consumption of antimicrobials in pigs, veal calves, and broilers in the Netherlands: Quantitative results of nationwide collection of data in 2011. / Bos, M.E.H.; Taverne, F.J.; van Geijlswijk, I.M.; Mouton, J.W.; Mevius, D.J.; Heederik, D.J.J.

In: PLoS ONE, Vol. 8, No. 10, e77525, 2013.

Research output: Contribution to journalArticleAcademicpeer-review

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T1 - Consumption of antimicrobials in pigs, veal calves, and broilers in the Netherlands: Quantitative results of nationwide collection of data in 2011

AU - Bos, M.E.H.

AU - Taverne, F.J.

AU - van Geijlswijk, I.M.

AU - Mouton, J.W.

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AB - In 2011, Dutch animal production sectors started recording veterinary antimicrobial consumption. These data are used by the Netherlands Veterinary Medicines Authority to create transparency in and define benchmark indicators for veterinary consumption of antimicrobials. This paper presents the results of sector wide consumption of antimicrobials, in the form of prescriptions or deliveries, for all pig, veal calf, and broiler farms. Data were used to calculate animal defined daily dosages per year (ADDD/Y) per pig or veal calf farm. For broiler farms, number of animal treatment days per year was calculated. Furthermore, data were used to calculate the consumption of specific antimicrobial classes per administration route per pig or veal calf farm. The distribution of antimicrobial consumption per farm varied greatly within and between farm categories. All categories, except for rosé starter farms, showed a highly right skewed distribution with a long tail. Median ADDD/Y values varied from 1.2 ADDD/Y for rosé finisher farms to 83.2 ADDD/Y for rosé starter farms, with 28.6 ADDD/Y for white veal calf farms. Median consumption in pig farms was 9.3 ADDD/Y for production pig farms and 3.0 ADDD/Y for slaughter pig farms. Median consumption in broiler farms was 20.9 ATD/Y. Regarding specific antimicrobial classes, fluoroquinolones were mainly used on veal calf farms, but in low quantities: P75 range was 0 – 0.99 ADDD/Y, and 0 – 0.04 ADDD/Y in pig farms. The P75 range for 3rd/4th-generation cephalosporins was 0 – 0.07 ADDD/Y for veal calf farms, and 0 – 0.1 ADDD/Y for pig farms. The insights obtained from these results, and the full transparency obtained by monitoring antimicrobial consumption per farm, will help reduce antimicrobial consumption and endorse antimicrobial stewardship. The wide and skewed distribution in consumption has important practical and methodological implications for benchmarking, surveillance and future analysis of trends.

KW - resistant staphylococcus-aureus

KW - escherichia-coli

KW - animals

KW - farmers

KW - health

KW - costs

KW - herds

KW - usage

KW - meat

KW - food

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