Conjugation of ATIII-Binding Pentasaccharides to Extend the Half-Life of Proteins: Long-Acting Insulin

M. de Kort, B. Gianotten, J. Wisse, E. Bos, M.H.M. Eppink, E. Mattaar, G. Vogel, W. Dokter, M. Honing, S. Vonsovic, M. Smit, J. Wijkmans, S. van Boeckel

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)
Original languageEnglish
Pages (from-to)1189-1193
JournalChemMedChem : chemistry enabling drug discovery
Volume3
Issue number8
DOIs
Publication statusPublished - 2008

Keywords

  • human serum-albumin
  • antithrombin-iii
  • fondaparinux sodium
  • heparin pentasaccharide
  • biological-properties
  • in-vivo
  • pegylation
  • analogs
  • drug
  • delivery

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