Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions

Izabella Bouhid de Aguiar, Martine Meireles, Antoine Bouchoux, Karin Schroën

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Clogging of porous media by soft particles has become a subject of extensive research in the last years and the understanding of the clogging mechanisms is of great importance for process optimization. The rise in the utilization of microfluidic devices brought the possibility to simulate membrane filtration and perform in situ observations of the pore clogging mechanisms with the aid of high speed cameras. In this work, we use microfluidic devices composed by an array of parallel channels to observe the clogging behavior of micrometer sized microgels. It is important to note that the microgels are larger than the pores/constrictions. We quantify the clog propensity in relation to the clogging position and particle size and find that the majority of the microgels clog at the first constriction independently of particle size and constriction entrance angle. We also quantify the variations in shape and volume (2D projection) of the microgels in relation to particle size and constriction entrance angle. We find that the degree of deformation increases with particle size and is dependent of constriction entrance angle, whereas, changes in volume do not depend on entrance angle.

LanguageEnglish
Article number9241
JournalScientific Reports
Volume9
DOIs
Publication statusPublished - 25 Jun 2019

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plugging
micrometers
constrictions
entrances
microfluidic devices
porosity
high speed cameras
projection
membranes
optimization

Cite this

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title = "Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions",
abstract = "Clogging of porous media by soft particles has become a subject of extensive research in the last years and the understanding of the clogging mechanisms is of great importance for process optimization. The rise in the utilization of microfluidic devices brought the possibility to simulate membrane filtration and perform in situ observations of the pore clogging mechanisms with the aid of high speed cameras. In this work, we use microfluidic devices composed by an array of parallel channels to observe the clogging behavior of micrometer sized microgels. It is important to note that the microgels are larger than the pores/constrictions. We quantify the clog propensity in relation to the clogging position and particle size and find that the majority of the microgels clog at the first constriction independently of particle size and constriction entrance angle. We also quantify the variations in shape and volume (2D projection) of the microgels in relation to particle size and constriction entrance angle. We find that the degree of deformation increases with particle size and is dependent of constriction entrance angle, whereas, changes in volume do not depend on entrance angle.",
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Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions. / Bouhid de Aguiar, Izabella; Meireles, Martine; Bouchoux, Antoine; Schroën, Karin.

In: Scientific Reports, Vol. 9, 9241, 25.06.2019.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Bouchoux, Antoine

AU - Schroën, Karin

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AB - Clogging of porous media by soft particles has become a subject of extensive research in the last years and the understanding of the clogging mechanisms is of great importance for process optimization. The rise in the utilization of microfluidic devices brought the possibility to simulate membrane filtration and perform in situ observations of the pore clogging mechanisms with the aid of high speed cameras. In this work, we use microfluidic devices composed by an array of parallel channels to observe the clogging behavior of micrometer sized microgels. It is important to note that the microgels are larger than the pores/constrictions. We quantify the clog propensity in relation to the clogging position and particle size and find that the majority of the microgels clog at the first constriction independently of particle size and constriction entrance angle. We also quantify the variations in shape and volume (2D projection) of the microgels in relation to particle size and constriction entrance angle. We find that the degree of deformation increases with particle size and is dependent of constriction entrance angle, whereas, changes in volume do not depend on entrance angle.

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