Confirmation of quantitative trait loci affecting fatness in chickens

D.G.J. Jennen; A.L.J. Vereijken; H. Bovenhuis; R.P.M.A. Crooijmans; J.J. van der Poel; M.A.M. Groenen

doi:10.1186/1297-9686-37-3-215

Confirmation of quantitative trait loci affecting fatness in chickens

D.G.J. Jennen, A.L.J. Vereijken, H. Bovenhuis, R.P.M.A. Crooijmans, J.J. van der Poel, M.A.M. Groenen

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

In this report we describe the analysis of an advanced intercross line (AIL) to confirm the quantitative trait locus (QTL) regions found for fatness traits in a previous study. QTL analysis was performed on chromosomes 1, 3, 4, 15, 18, and 27. The AIL was created by random intercrossing in each generation from generation 2 (G 2) onwards until generation 9 (G 9) was reached. QTL for abdominal fat weight (AFW) and/or percentage abdominal fat (AF%) on chromosomes 1, 3 and 27 were confirmed in the G 9 population. In addition, evidence for QTL for body weight at the age of 5 (BW5) and 7 (BW7) weeks and for the percentage of intramuscular fat (IF%) were found on chromosomes 1, 3, 15, and 27. Significant evidence for QTL was detected on chromosome 1 for BW5 and BW7. Suggestive evidence was found on chromosome 1 for AFW, AF% and IF%, on chromosome 15 for BW5, and on chromosome 27 for AF% and IF%. Furthermore, evidence on the chromosome-wise level was found on chromosome 3 for AFW, AF%, and BW7 and on chromosome 27 for BW5. For chromosomes 4 and 18, test statistics did not exceed the significance threshold

Original language	English
Pages (from-to)	215-228
Journal	Genetics, Selection, Evolution
Volume	37
Issue number	2
DOIs	https://doi.org/10.1186/1297-9686-37-3-215
Publication status	Published - 2005

Keywords

advanced intercross lines
whole genome scan
affecting body-weight
composition maps
carcass traits
milk-yield
qtl
growth
population
broilers

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10.1186/1297-9686-37-3-215

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title = "Confirmation of quantitative trait loci affecting fatness in chickens",

abstract = "In this report we describe the analysis of an advanced intercross line (AIL) to confirm the quantitative trait locus (QTL) regions found for fatness traits in a previous study. QTL analysis was performed on chromosomes 1, 3, 4, 15, 18, and 27. The AIL was created by random intercrossing in each generation from generation 2 (G 2) onwards until generation 9 (G 9) was reached. QTL for abdominal fat weight (AFW) and/or percentage abdominal fat (AF%) on chromosomes 1, 3 and 27 were confirmed in the G 9 population. In addition, evidence for QTL for body weight at the age of 5 (BW5) and 7 (BW7) weeks and for the percentage of intramuscular fat (IF%) were found on chromosomes 1, 3, 15, and 27. Significant evidence for QTL was detected on chromosome 1 for BW5 and BW7. Suggestive evidence was found on chromosome 1 for AFW, AF% and IF%, on chromosome 15 for BW5, and on chromosome 27 for AF% and IF%. Furthermore, evidence on the chromosome-wise level was found on chromosome 3 for AFW, AF%, and BW7 and on chromosome 27 for BW5. For chromosomes 4 and 18, test statistics did not exceed the significance threshold",

keywords = "advanced intercross lines, whole genome scan, affecting body-weight, composition maps, carcass traits, milk-yield, qtl, growth, population, broilers",

author = "D.G.J. Jennen and A.L.J. Vereijken and H. Bovenhuis and R.P.M.A. Crooijmans and {van der Poel}, J.J. and M.A.M. Groenen",

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T1 - Confirmation of quantitative trait loci affecting fatness in chickens

AU - Jennen, D.G.J.

AU - Vereijken, A.L.J.

AU - Bovenhuis, H.

AU - Crooijmans, R.P.M.A.

AU - van der Poel, J.J.

AU - Groenen, M.A.M.

PY - 2005

Y1 - 2005

N2 - In this report we describe the analysis of an advanced intercross line (AIL) to confirm the quantitative trait locus (QTL) regions found for fatness traits in a previous study. QTL analysis was performed on chromosomes 1, 3, 4, 15, 18, and 27. The AIL was created by random intercrossing in each generation from generation 2 (G 2) onwards until generation 9 (G 9) was reached. QTL for abdominal fat weight (AFW) and/or percentage abdominal fat (AF%) on chromosomes 1, 3 and 27 were confirmed in the G 9 population. In addition, evidence for QTL for body weight at the age of 5 (BW5) and 7 (BW7) weeks and for the percentage of intramuscular fat (IF%) were found on chromosomes 1, 3, 15, and 27. Significant evidence for QTL was detected on chromosome 1 for BW5 and BW7. Suggestive evidence was found on chromosome 1 for AFW, AF% and IF%, on chromosome 15 for BW5, and on chromosome 27 for AF% and IF%. Furthermore, evidence on the chromosome-wise level was found on chromosome 3 for AFW, AF%, and BW7 and on chromosome 27 for BW5. For chromosomes 4 and 18, test statistics did not exceed the significance threshold

AB - In this report we describe the analysis of an advanced intercross line (AIL) to confirm the quantitative trait locus (QTL) regions found for fatness traits in a previous study. QTL analysis was performed on chromosomes 1, 3, 4, 15, 18, and 27. The AIL was created by random intercrossing in each generation from generation 2 (G 2) onwards until generation 9 (G 9) was reached. QTL for abdominal fat weight (AFW) and/or percentage abdominal fat (AF%) on chromosomes 1, 3 and 27 were confirmed in the G 9 population. In addition, evidence for QTL for body weight at the age of 5 (BW5) and 7 (BW7) weeks and for the percentage of intramuscular fat (IF%) were found on chromosomes 1, 3, 15, and 27. Significant evidence for QTL was detected on chromosome 1 for BW5 and BW7. Suggestive evidence was found on chromosome 1 for AFW, AF% and IF%, on chromosome 15 for BW5, and on chromosome 27 for AF% and IF%. Furthermore, evidence on the chromosome-wise level was found on chromosome 3 for AFW, AF%, and BW7 and on chromosome 27 for BW5. For chromosomes 4 and 18, test statistics did not exceed the significance threshold

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KW - whole genome scan

KW - affecting body-weight

KW - composition maps

KW - carcass traits

KW - milk-yield

KW - qtl

KW - growth

KW - population

KW - broilers

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DO - 10.1186/1297-9686-37-3-215

M3 - Article

SN - 0999-193X

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SP - 215

EP - 228

JO - Genetics, Selection, Evolution

JF - Genetics, Selection, Evolution

IS - 2

ER -

Confirmation of quantitative trait loci affecting fatness in chickens

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Keywords

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