Configuration of bioreactors

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)


Lab-scale stirred-tank bioreactors (0.2–20 l) are used for fundamental research on animal cells and in process development and troubleshooting for large-scale production. In this chapter, different configurations of bioreactor systems are shortly discussed and setting up these different configurations is described. In addition, online measurement and control of bioreactor parameters is described, with special attention to controller settings (PID) and online measurement of oxygen consumption and carbon dioxide production. Finally, methods for determining the oxygen transfer coefficient are described.
Original languageEnglish
Title of host publicationMethods in molecular biology
EditorsR. Pörtner
Number of pages341
Publication statusPublished - 2014

Publication series

NameMethods in molecular biology

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    Martens, D. E., van den End, E. J., & Streefland, M. (2014). Configuration of bioreactors. In R. Pörtner (Ed.), Methods in molecular biology (pp. 285-311). (Methods in molecular biology; No. 1104).