Comprehensive two-dimensional gas chromatography for the analysis of organohalogenated micro-contaminants

P. Korytar; P. Haglund; J. de Boer; U.A.Th. Brinkman

doi:10.1016/j.trac.2005.12.003

Comprehensive two-dimensional gas chromatography for the analysis of organohalogenated micro-contaminants

P. Korytar, P. Haglund, J. de Boer, U.A.Th. Brinkman

Toxicology

Research output: Contribution to journal › Article › Academic › peer-review

41 Citations (Scopus)

Abstract

We explain the principles of comprehensive two-dimensional gas chromatography (GC × GC), and discuss key instrumental aspects - with emphasis on column combinations and mass spectrometric detection. As the main item of interest, we review the potential of GC × GC for the analysis of organohalogenated micro-contaminants, and highlight its superiority over conventional 1D-GC. We present results for 12 compound classes, including polychlorinated biphenyls, dibenzo-p-dioxins and furans, and n-alkanes, toxaphene and polybrominated diphenyl ethers. We draw attention to target analysis as well as within-class and between-class separations

Original language	English
Pages (from-to)	373-396
Journal	TrAC : Trends in Analytical Chemistry
Volume	25
Issue number	4
DOIs	https://doi.org/10.1016/j.trac.2005.12.003
Publication status	Published - 2006

Keywords

flight mass-spectrometry
polybrominated diphenyl ethers
electron-capture detection
gc x gc
chiral polychlorinated-biphenyls
dibenzo-p-dioxins
structural information
chlorinated bornanes
simple nomenclature
food samples

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10.1016/j.trac.2005.12.003

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title = "Comprehensive two-dimensional gas chromatography for the analysis of organohalogenated micro-contaminants",

abstract = "We explain the principles of comprehensive two-dimensional gas chromatography (GC × GC), and discuss key instrumental aspects - with emphasis on column combinations and mass spectrometric detection. As the main item of interest, we review the potential of GC × GC for the analysis of organohalogenated micro-contaminants, and highlight its superiority over conventional 1D-GC. We present results for 12 compound classes, including polychlorinated biphenyls, dibenzo-p-dioxins and furans, and n-alkanes, toxaphene and polybrominated diphenyl ethers. We draw attention to target analysis as well as within-class and between-class separations",

keywords = "flight mass-spectrometry, polybrominated diphenyl ethers, electron-capture detection, gc x gc, chiral polychlorinated-biphenyls, dibenzo-p-dioxins, structural information, chlorinated bornanes, simple nomenclature, food samples",

author = "P. Korytar and P. Haglund and {de Boer}, J. and U.A.Th. Brinkman",

year = "2006",

doi = "10.1016/j.trac.2005.12.003",

language = "English",

volume = "25",

pages = "373--396",

journal = "TrAC : Trends in Analytical Chemistry",

issn = "0165-9936",

publisher = "Elsevier",

number = "4",

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TY - JOUR

T1 - Comprehensive two-dimensional gas chromatography for the analysis of organohalogenated micro-contaminants

AU - Korytar, P.

AU - Haglund, P.

AU - de Boer, J.

AU - Brinkman, U.A.Th.

PY - 2006

Y1 - 2006

N2 - We explain the principles of comprehensive two-dimensional gas chromatography (GC × GC), and discuss key instrumental aspects - with emphasis on column combinations and mass spectrometric detection. As the main item of interest, we review the potential of GC × GC for the analysis of organohalogenated micro-contaminants, and highlight its superiority over conventional 1D-GC. We present results for 12 compound classes, including polychlorinated biphenyls, dibenzo-p-dioxins and furans, and n-alkanes, toxaphene and polybrominated diphenyl ethers. We draw attention to target analysis as well as within-class and between-class separations

AB - We explain the principles of comprehensive two-dimensional gas chromatography (GC × GC), and discuss key instrumental aspects - with emphasis on column combinations and mass spectrometric detection. As the main item of interest, we review the potential of GC × GC for the analysis of organohalogenated micro-contaminants, and highlight its superiority over conventional 1D-GC. We present results for 12 compound classes, including polychlorinated biphenyls, dibenzo-p-dioxins and furans, and n-alkanes, toxaphene and polybrominated diphenyl ethers. We draw attention to target analysis as well as within-class and between-class separations

KW - flight mass-spectrometry

KW - polybrominated diphenyl ethers

KW - electron-capture detection

KW - gc x gc

KW - chiral polychlorinated-biphenyls

KW - dibenzo-p-dioxins

KW - structural information

KW - chlorinated bornanes

KW - simple nomenclature

KW - food samples

U2 - 10.1016/j.trac.2005.12.003

DO - 10.1016/j.trac.2005.12.003

M3 - Article

SN - 0165-9936

VL - 25

SP - 373

EP - 396

JO - TrAC : Trends in Analytical Chemistry

JF - TrAC : Trends in Analytical Chemistry

IS - 4

ER -

Comprehensive two-dimensional gas chromatography for the analysis of organohalogenated micro-contaminants

Abstract

Keywords

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