Competitive selection of lactic acid bacteria that persist in the human oral cavity

J. Snel, M.L. Marco, F. Kingma, W.M. Noordman, J. Rademaker, M. Kleerebezem

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Lactic acid bacteria (LAB) might offer opportunities as oral probiotics provided candidate strains persist in the mouth. After intake of a mixture of 69 LAB, strains of Lactobacillus fermentum and Lactobacillus salivarius were especially recovered. Coaggregation with other microbes is likely not a prerequisite for persistence since L. salivarius strongly coaggregated with typical oral cavity isolates, whereas L. fermentum failed to display this phenotype.
Original languageEnglish
Pages (from-to)8445-8450
JournalApplied and Environmental Microbiology
Issue number23
Publication statusPublished - 2011



  • lactobacillus-reuteri
  • in-vitro
  • probiotics
  • coaggregation
  • colonization
  • streptococci
  • health

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