TY - JOUR
T1 - Comparison of comprehensive fatty acid profile from different regions in Chinese human milk project (CHMP) study
AU - Zhu, Huiquan
AU - Wang, Xiaodan
AU - Li, Kaifeng
AU - Zhang, Yuchen
AU - Fauconnier, Marie Laure
AU - Chen, Baorong
AU - Zhang, Shuwen
AU - Jiang, Shilong
AU - Pang, Xiaoyang
AU - Lv, Jiaping
PY - 2024/8
Y1 - 2024/8
N2 - In this study, we aimed to detect the comprehensive fatty acid (FA) profile in human milk, including total fatty acids (total FAs), Sn-2 fatty acids (Sn-2 FAs), and phospholipid fatty acids (PLFAs), and further analyzed the influence of the sampling regions on human milk FA profile. The results showed that oleic acid (C18:1n9c), palmitic acid (C16:0), and linoleic acid (C18:2n6c) were the main FA species in total FAs, and Sn-2 C16:0 was the dominant Sn-2 FA species. Moreover, the PLFAs were mainly comprised of PL C16:0, PL stearic acid (PL C18:0), PL C18:1n9c, and PL C18:2n6c. Furthermore, FAs showed geographical differences, such as the highest content of linolenic acid (C18:3n3) and docosahexaenoic acid (C22:6n3) of total FAs was observed in Lanzhou and Weihai, respectively. Therefore, these results provide more FA data for the Chinese human milk database, and further enrich the theoretical information for the development of infant formula.
AB - In this study, we aimed to detect the comprehensive fatty acid (FA) profile in human milk, including total fatty acids (total FAs), Sn-2 fatty acids (Sn-2 FAs), and phospholipid fatty acids (PLFAs), and further analyzed the influence of the sampling regions on human milk FA profile. The results showed that oleic acid (C18:1n9c), palmitic acid (C16:0), and linoleic acid (C18:2n6c) were the main FA species in total FAs, and Sn-2 C16:0 was the dominant Sn-2 FA species. Moreover, the PLFAs were mainly comprised of PL C16:0, PL stearic acid (PL C18:0), PL C18:1n9c, and PL C18:2n6c. Furthermore, FAs showed geographical differences, such as the highest content of linolenic acid (C18:3n3) and docosahexaenoic acid (C22:6n3) of total FAs was observed in Lanzhou and Weihai, respectively. Therefore, these results provide more FA data for the Chinese human milk database, and further enrich the theoretical information for the development of infant formula.
U2 - 10.1016/j.idairyj.2024.105947
DO - 10.1016/j.idairyj.2024.105947
M3 - Article
AN - SCOPUS:85190136469
SN - 0958-6946
VL - 155
JO - International Dairy Journal
JF - International Dairy Journal
M1 - 105947
ER -