This paper aims to examine and compare the interactions between policy to combat illegal logging (FLEGT VPA) and avoiding deforestation and forest degradation (REDD+) in Cameroon and the Republic of the Congo by applying an institutional interaction approach. Several interactions have occurred between the two regimes, and more interactions are expected. In both countries, the process for developing the VPA has served as a policy model for designing elements of REDD+. Overlaps in issue-areas and membership triggered these interactions. Implementation of the VPA is also expected to result in positive behavioural change among forest stakeholders that could in turn have positive impacts on REDD+. There are also disruptive interactions, such as the slow pace of VPA implementation affecting REDD+ progress in both countries. Furthermore, there is substantial similarity in terms of the nature and quality of interactions between Cameroon and Congo. Building understanding and exchange of information among stakeholders and request for assistance and jurisdictional delimitation could enhance synergies and mitigate disruptive interactions between the two regimes in both countries.