Combined effort of alcohol consumption and lifestyle behaviors on risk of type 2 diabetes

M.M. Joosten, D.E. Grobbee, D.L. van der A, W.M. Verschuren, H.F.J. Hendriks, J.W.J. Beulens

Research output: Contribution to journalArticleAcademicpeer-review

55 Citations (Scopus)


ackground: It has been suggested that the inverse association between alcohol and type 2 diabetes could be explained by moderate drinkers’ healthier lifestyles. Objective: We studied whether moderate alcohol consumption is associated with a lower risk of type 2 diabetes in adults with combined low-risk lifestyle behaviors. Design: We prospectively examined 35,625 adults of the Dutch European Prospective Investigation into Cancer and Nutrition (EPIC-NL) cohort aged 20–70 y, who were free of diabetes, cardiovascular disease, and cancer at baseline (1993–1997). In addition to moderate alcohol consumption (women: 5.0–14.9 g/d; men: 5.0–29.9 g/d), we defined low-risk categories of 4 lifestyle behaviors: optimal weight [body mass index (in kg/m2)
Original languageEnglish
Pages (from-to)1777-1783
JournalAmerican Journal of Clinical Nutrition
Issue number6
Publication statusPublished - 2010


  • coronary-heart-disease
  • physical-activity questionnaire
  • food frequency questionnaire
  • postmenopausal women
  • insulin sensitivity
  • relative validity
  • mellitus
  • diet
  • atherosclerosis
  • reproducibility

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