Coffee consumption is inversely associated with cognitive decline in elderly European men: the FINE Study

B.M. van Gelder, B. Buijsse, M.J. Tijhuis, S. Kalmijn, S. Giampaoli, A. Nissinen, D. Kromhout

Research output: Contribution to journalArticleAcademicpeer-review

149 Citations (Scopus)

Abstract

Objective: To investigate whether coffee consumption is associated with 10-year cognitive decline in elderly men, as results of previous studies obtained hitherto have been controversial and prospective information on this association has been lacking. Design, subjects and setting: Six hundred and seventy six healthy men born between 1900 and 1920 from Finland, Italy and the Netherlands participated in a 10-year prospective cohort study. Cognitive functioning was assessed using the Mini-Mental State Examination (0¿30 points, with a higher score indicating better cognitive performance). Coffee consumption was estimated in cups per day. A mixed longitudinal model was used to investigate the association between baseline coffee consumption and 10-year cognitive decline. Multiple adjustments were made. Results: Men who consumed coffee had a 10-year cognitive decline of 1.2 points (4%). Non-consumers had an additional decline of 1.4 points (P
Original languageEnglish
Pages (from-to)226-232
JournalEuropean Journal of Clinical Nutrition
Volume61
Issue number2
DOIs
Publication statusPublished - 2007

Keywords

  • risk-factors
  • alzheimers-disease
  • state-examination
  • caffeine
  • humans
  • netherlands
  • performance
  • adenosine
  • finland
  • age

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