Clickable elastins : elastin-like polypeptides functionalized with azide or alkyne groups

R.L.M. Teeuwen, S.S. van Berkel, T.H.H. van Dulmen, S. Schoffelen, S.A. Meeuwissen, H. Zuilhof, F.A. de Wolf, J.C.M. van Hest

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Abstract

Elastin-like polypeptides (ELPs) functionalized with azide or alkyne groups were produced biosynthetically and coupled via the Cu-catalyzed azide¿alkyne cycloaddition to a variety of (bio)molecules.
Original languageEnglish
Pages (from-to)4022-4024
JournalChemical Communications
Volume2009
Issue number27
DOIs
Publication statusPublished - 2009

Keywords

  • protein-based polymers
  • pennsylvania green fluorophore
  • in-vivo
  • block-copolymers
  • phase-transition
  • responsive polymers
  • escherichia-coli
  • cell-adhesion
  • solid tumors
  • purification

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  • Cite this

    Teeuwen, R. L. M., van Berkel, S. S., van Dulmen, T. H. H., Schoffelen, S., Meeuwissen, S. A., Zuilhof, H., ... van Hest, J. C. M. (2009). Clickable elastins : elastin-like polypeptides functionalized with azide or alkyne groups. Chemical Communications, 2009(27), 4022-4024. https://doi.org/10.1039/b903903a