Clickable elastins : elastin-like polypeptides functionalized with azide or alkyne groups

R.L.M. Teeuwen, S.S. van Berkel, T.H.H. van Dulmen, S. Schoffelen, S.A. Meeuwissen, H. Zuilhof, F.A. de Wolf, J.C.M. van Hest

Research output: Contribution to journal › Article › Academic › peer-review

33 Citations (Scopus)

Abstract

Elastin-like polypeptides (ELPs) functionalized with azide or alkyne groups were produced biosynthetically and coupled via the Cu-catalyzed azide¿alkyne cycloaddition to a variety of (bio)molecules.
Original languageEnglish
Pages (from-to)4022-4024
JournalChemical Communications
Volume2009
Issue number27
DOIs
Publication statusPublished - 2009

Keywords

  • protein-based polymers
  • pennsylvania green fluorophore
  • in-vivo
  • block-copolymers
  • phase-transition
  • responsive polymers
  • escherichia-coli
  • cell-adhesion
  • solid tumors
  • purification

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    Teeuwen, R. L. M., van Berkel, S. S., van Dulmen, T. H. H., Schoffelen, S., Meeuwissen, S. A., Zuilhof, H., ... van Hest, J. C. M. (2009). Clickable elastins : elastin-like polypeptides functionalized with azide or alkyne groups. Chemical Communications, 2009(27), 4022-4024. https://doi.org/10.1039/b903903a