Classification and evaluation of microfluidic devices for continuous suspension fractionation

Research output: Contribution to journalArticleAcademicpeer-review

54 Citations (Scopus)

Abstract

Membrane processes are well-known for separating and fractionating suspensions in many industries, but suffer from particle accumulation on the membrane surface. Currently, there are new developments using microfluidic devices for cell/DNA sorting and fractionation. We anticipate these devices are also applicable to fractionation of polydisperse and concentrated suspensions (e.g. foods), and may potentially have fewer problems with particle accumulation compared to membranes. This review article presents an overview of relevant microfluidic devices. We focus on their performance with respect to concentrated suspensions, as one finds in food industry. We give quantitative estimates on their yield, selectivity, and the potential for large-scale application. From this evaluation follows that deterministic ratchets seem most promising.
Original languageEnglish
Pages (from-to)53-66
JournalAdvances in Colloid and Interface Science
Volume142
Issue number1/2
DOIs
Publication statusPublished - 2008

Keywords

  • field-flow fractionation
  • deterministic lateral displacement
  • continuous particle separation
  • colloidal particles
  • dielectrophoretic separation
  • membrane
  • size
  • manipulation
  • microfiltration
  • filtration

Fingerprint Dive into the research topics of 'Classification and evaluation of microfluidic devices for continuous suspension fractionation'. Together they form a unique fingerprint.

  • Cite this