Circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands, 2006-2016

Saskia A. Bergervoet, Sylvia B.E. Pritz-Verschuren, Jose L. Gonzales, Alex Bossers, Marjolein J. Poen, Jayeeta Dutta, Zenab Khan, Divya Kriti, Harm van Bakel, Ruth Bouwstra, Ron A.M. Fouchier, Nancy Beerens*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Abstract

In this study, we explore the circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands. Surveillance data collected between 2006 and 2016 was used to evaluate subtype diversity, spatiotemporal distribution and genetic relationships between wild bird and poultry viruses. We observed close species-dependent associations among hemagglutinin and neuraminidase subtypes. Not all subtypes detected in wild birds were found in poultry, suggesting transmission to poultry is selective and likely depends on viral factors that determine host range restriction. Subtypes commonly detected in poultry were in wild birds most frequently detected in mallards and geese. Different temporal patterns in virus prevalence were observed between wild bird species. Virus detections in domestic ducks coincided with the prevalence peak in wild ducks, whereas virus detections in other poultry types were made throughout the year. Genetic analysis of the surface genes demonstrated that most poultry viruses were related to locally circulating wild bird viruses, but no direct spatiotemporal link was observed. Results indicate prolonged undetected virus circulation and frequent reassortment events with local and newly introduced viruses within the wild bird population. Increased knowledge on LPAI virus circulation can be used to improve surveillance strategies.

Original languageEnglish
Article number13681
Number of pages1
JournalScientific Reports
Volume9
Issue number1
DOIs
Publication statusPublished - 23 Sep 2019

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Influenza in Birds
Poultry
Orthomyxoviridae
Netherlands
Birds
Viruses
Ducks
Geese
Host Specificity
Hemagglutinins
Neuraminidase

Cite this

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title = "Circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands, 2006-2016",
abstract = "In this study, we explore the circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands. Surveillance data collected between 2006 and 2016 was used to evaluate subtype diversity, spatiotemporal distribution and genetic relationships between wild bird and poultry viruses. We observed close species-dependent associations among hemagglutinin and neuraminidase subtypes. Not all subtypes detected in wild birds were found in poultry, suggesting transmission to poultry is selective and likely depends on viral factors that determine host range restriction. Subtypes commonly detected in poultry were in wild birds most frequently detected in mallards and geese. Different temporal patterns in virus prevalence were observed between wild bird species. Virus detections in domestic ducks coincided with the prevalence peak in wild ducks, whereas virus detections in other poultry types were made throughout the year. Genetic analysis of the surface genes demonstrated that most poultry viruses were related to locally circulating wild bird viruses, but no direct spatiotemporal link was observed. Results indicate prolonged undetected virus circulation and frequent reassortment events with local and newly introduced viruses within the wild bird population. Increased knowledge on LPAI virus circulation can be used to improve surveillance strategies.",
author = "Bergervoet, {Saskia A.} and Pritz-Verschuren, {Sylvia B.E.} and Gonzales, {Jose L.} and Alex Bossers and Poen, {Marjolein J.} and Jayeeta Dutta and Zenab Khan and Divya Kriti and {van Bakel}, Harm and Ruth Bouwstra and Fouchier, {Ron A.M.} and Nancy Beerens",
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language = "English",
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Circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands, 2006-2016. / Bergervoet, Saskia A.; Pritz-Verschuren, Sylvia B.E.; Gonzales, Jose L.; Bossers, Alex; Poen, Marjolein J.; Dutta, Jayeeta; Khan, Zenab; Kriti, Divya; van Bakel, Harm; Bouwstra, Ruth; Fouchier, Ron A.M.; Beerens, Nancy.

In: Scientific Reports, Vol. 9, No. 1, 13681 , 23.09.2019.

Research output: Contribution to journalArticleAcademicpeer-review

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T1 - Circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands, 2006-2016

AU - Bergervoet, Saskia A.

AU - Pritz-Verschuren, Sylvia B.E.

AU - Gonzales, Jose L.

AU - Bossers, Alex

AU - Poen, Marjolein J.

AU - Dutta, Jayeeta

AU - Khan, Zenab

AU - Kriti, Divya

AU - van Bakel, Harm

AU - Bouwstra, Ruth

AU - Fouchier, Ron A.M.

AU - Beerens, Nancy

PY - 2019/9/23

Y1 - 2019/9/23

N2 - In this study, we explore the circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands. Surveillance data collected between 2006 and 2016 was used to evaluate subtype diversity, spatiotemporal distribution and genetic relationships between wild bird and poultry viruses. We observed close species-dependent associations among hemagglutinin and neuraminidase subtypes. Not all subtypes detected in wild birds were found in poultry, suggesting transmission to poultry is selective and likely depends on viral factors that determine host range restriction. Subtypes commonly detected in poultry were in wild birds most frequently detected in mallards and geese. Different temporal patterns in virus prevalence were observed between wild bird species. Virus detections in domestic ducks coincided with the prevalence peak in wild ducks, whereas virus detections in other poultry types were made throughout the year. Genetic analysis of the surface genes demonstrated that most poultry viruses were related to locally circulating wild bird viruses, but no direct spatiotemporal link was observed. Results indicate prolonged undetected virus circulation and frequent reassortment events with local and newly introduced viruses within the wild bird population. Increased knowledge on LPAI virus circulation can be used to improve surveillance strategies.

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