Chromosome Segregation: Organizing Overlap at the Midzone

M.E. Janson; P.T. Tran

doi:10.1016/j.cub.2008.02.012

Chromosome Segregation: Organizing Overlap at the Midzone

M.E. Janson, P.T. Tran

Laboratory of Cell Biology

Research output: Contribution to journal › Editorial › Academic › peer-review

1 Citation (Scopus)

Abstract

Sets of overlapping microtubules support the segregation of chromosomes by linking the poles of mitotic spindles. Recent work examines the effect of putting these linkages under pressure by the activation of dicentric chromosomes and sheds new light on the structural role of several well-known spindle midzone proteins

Original language	English
Pages (from-to)	R308-R311
Journal	Current Biology
Volume	18
Issue number	7
DOIs	https://doi.org/10.1016/j.cub.2008.02.012
Publication status	Published - 2008

Keywords

fission yeast
spindle midzone
microtubules
cytokinesis
dynamics
binding
mitosis
arrays
ase1p
prc1

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title = "Chromosome Segregation: Organizing Overlap at the Midzone",

abstract = "Sets of overlapping microtubules support the segregation of chromosomes by linking the poles of mitotic spindles. Recent work examines the effect of putting these linkages under pressure by the activation of dicentric chromosomes and sheds new light on the structural role of several well-known spindle midzone proteins",

keywords = "fission yeast, spindle midzone, microtubules, cytokinesis, dynamics, binding, mitosis, arrays, ase1p, prc1",

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AU - Janson, M.E.

AU - Tran, P.T.

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AB - Sets of overlapping microtubules support the segregation of chromosomes by linking the poles of mitotic spindles. Recent work examines the effect of putting these linkages under pressure by the activation of dicentric chromosomes and sheds new light on the structural role of several well-known spindle midzone proteins

KW - fission yeast

KW - spindle midzone

KW - microtubules

KW - cytokinesis

KW - dynamics

KW - binding

KW - mitosis

KW - arrays

KW - ase1p

KW - prc1

U2 - 10.1016/j.cub.2008.02.012

DO - 10.1016/j.cub.2008.02.012

M3 - Editorial

VL - 18

SP - R308-R311

JO - Current Biology

JF - Current Biology

SN - 0960-9822

IS - 7

ER -