Chromosome Segregation: Organizing Overlap at the Midzone

M.E. Janson, P.T. Tran

Research output: Contribution to journalEditorialAcademicpeer-review

1 Citation (Scopus)

Abstract

Sets of overlapping microtubules support the segregation of chromosomes by linking the poles of mitotic spindles. Recent work examines the effect of putting these linkages under pressure by the activation of dicentric chromosomes and sheds new light on the structural role of several well-known spindle midzone proteins
Original languageEnglish
Pages (from-to)R308-R311
JournalCurrent Biology
Volume18
Issue number7
DOIs
Publication statusPublished - 2008

Fingerprint

Chromosome Segregation
mitotic spindle apparatus
Spindle Apparatus
chromosome segregation
Chromosomes
Microtubules
microtubules
linkage (genetics)
chromosomes
Pressure
Poles
Proteins
proteins
Chemical activation

Keywords

  • fission yeast
  • spindle midzone
  • microtubules
  • cytokinesis
  • dynamics
  • binding
  • mitosis
  • arrays
  • ase1p
  • prc1

Cite this

Janson, M.E. ; Tran, P.T. / Chromosome Segregation: Organizing Overlap at the Midzone. In: Current Biology. 2008 ; Vol. 18, No. 7. pp. R308-R311.
@article{5b0ce631af6e4e1a9c9a198b1c54371a,
title = "Chromosome Segregation: Organizing Overlap at the Midzone",
abstract = "Sets of overlapping microtubules support the segregation of chromosomes by linking the poles of mitotic spindles. Recent work examines the effect of putting these linkages under pressure by the activation of dicentric chromosomes and sheds new light on the structural role of several well-known spindle midzone proteins",
keywords = "fission yeast, spindle midzone, microtubules, cytokinesis, dynamics, binding, mitosis, arrays, ase1p, prc1",
author = "M.E. Janson and P.T. Tran",
year = "2008",
doi = "10.1016/j.cub.2008.02.012",
language = "English",
volume = "18",
pages = "R308--R311",
journal = "Current Biology",
issn = "0960-9822",
publisher = "Elsevier",
number = "7",

}

Chromosome Segregation: Organizing Overlap at the Midzone. / Janson, M.E.; Tran, P.T.

In: Current Biology, Vol. 18, No. 7, 2008, p. R308-R311.

Research output: Contribution to journalEditorialAcademicpeer-review

TY - JOUR

T1 - Chromosome Segregation: Organizing Overlap at the Midzone

AU - Janson, M.E.

AU - Tran, P.T.

PY - 2008

Y1 - 2008

N2 - Sets of overlapping microtubules support the segregation of chromosomes by linking the poles of mitotic spindles. Recent work examines the effect of putting these linkages under pressure by the activation of dicentric chromosomes and sheds new light on the structural role of several well-known spindle midzone proteins

AB - Sets of overlapping microtubules support the segregation of chromosomes by linking the poles of mitotic spindles. Recent work examines the effect of putting these linkages under pressure by the activation of dicentric chromosomes and sheds new light on the structural role of several well-known spindle midzone proteins

KW - fission yeast

KW - spindle midzone

KW - microtubules

KW - cytokinesis

KW - dynamics

KW - binding

KW - mitosis

KW - arrays

KW - ase1p

KW - prc1

U2 - 10.1016/j.cub.2008.02.012

DO - 10.1016/j.cub.2008.02.012

M3 - Editorial

VL - 18

SP - R308-R311

JO - Current Biology

JF - Current Biology

SN - 0960-9822

IS - 7

ER -