Chiral building blocks from biomass : 2,5-diamino-2,5-dideoxy-1,4-3,6-dianhydroiditol

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45 Citations (Scopus)


An efficient route towards the synthesis of 2,5-diamino-2,5-dideoxy-1,4-3,6-dianhydroiditol 4 has been developed resulting in significant improvements in both isolated yields and purity when compared to literature procedures. As a consequence, resin-grade 2,5-diamino-2,5-dideoxy-1,4-3,6-dianhydroiditol 4 has become available for laboratory scale step-growth polymer synthesis. Additionally, an interesting renewable chiral 2-amino-2-deoxy-1,4-3,6-dianhydroiditol 10, has been isolated.
Original languageEnglish
Pages (from-to)383-389
Issue number2
Publication statusPublished - 2011


  • derivatives
  • isosorbide

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