Chicks from a high and low feather pecking line of laying hens differ in apomorphine sensitivity

Y.M. van Hierden, J.M. Koolhaas, L. Kost'al, P. Vyboh, M. Sedlackova, M. Rajman, M. Jurani, S.M. Korte

    Research output: Contribution to journalArticleAcademicpeer-review

    26 Citations (Scopus)

    Abstract

    Proactive rodents show a larger behavioral response to apomorphine (APO) than reactive copers, suggesting a more sensitive DA system in proactive individuals. Previously, chicks from a high feather pecking (HFP) and low feather pecking line (LFP) have been suggested to display a proactive and reactive coping strategy, respectively. Therefore, at approximately 4 weeks of age, the behavior of 48 LFP and 48 HFP chicks in response to an APO injection was studied using an open field. Another objective of the present study was to determine whether behavioral variation (in an open field) between HFP and LFP birds, after APO injection, is also reflected by variation of D1 and D2 receptor densities in the brain. Receptor binding capacities were assessed by measuring specific binding of tritiated D1 and D2 receptor ligands in different regions of the brain of control HFP and LFP chicks. In the present study, it is shown that indeed HFP chicks display a more enhanced behavioral response to acute APO treatment (0.5 mg/kg BW) than LFP birds in an open field. This difference was not reflected by variation of D1 and D2 receptor densities in the brain between both lines.
    Original languageEnglish
    Pages (from-to)471-477
    JournalPhysiology and Behavior
    Volume84
    Issue number3
    DOIs
    Publication statusPublished - 2005

    Keywords

    • wistar rats differ
    • dopamine turnover
    • manual restraint
    • behavior
    • serotonin
    • haloperidol
    • catecholamine
    • involvement
    • receptors
    • recovery

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  • Cite this

    van Hierden, Y. M., Koolhaas, J. M., Kost'al, L., Vyboh, P., Sedlackova, M., Rajman, M., Jurani, M., & Korte, S. M. (2005). Chicks from a high and low feather pecking line of laying hens differ in apomorphine sensitivity. Physiology and Behavior, 84(3), 471-477. https://doi.org/10.1016/j.physbeh.2005.01.015