Changes in body composition during chemotherapy in women with breast cancer

M.M.G.A. van den Berg, R.M. Winkels, L.M. Kamps, P.J.M. Hulshof, M. Visser, H. van Laarhoven, J.H.M. de Vries, E. Kampman

Research output: Contribution to conferencePoster


Background Weight gain can be an important side-effect of chemotherapy for women with breast cancer. This increase IS EXPECTED TO CONSIST mainly OF fat mass, with losses of or no change in muscle mass. These changes can affect PHYSICAL FUNCTION AND quality of life and may increase the risk of disease recurrence, SUCH AS cardiovascular disease and diabetes. Results This poster shows the preliminary results on body composition of the first Participants, Objective Within the COBRA-study, we will study changes in body composition in breast cancer patients during chemotherapy in comparison to women without breast CANCER. This poster provides preliminary data on THE 6 MONTH changes in body composition in the first participants of the Cobra-study. Methods The COBRA-study • Multi-centre, observational study among 300 breast cancer patients undergoing chemotherapy and a comparison group of 300 women without breast cancer. • 4 moments of measurement, see figure 1. • Measurements on body composition (DEXA&BIA), muscle strength, dietary intake/food references, physical activity and quality of life and perceptions of participants on these subjects. This poster • Preliminary results of the first included participants on body composition during chemotherapy: DEXA-scans, Bioelectrical Impedance Analysis (BIA) AND Hip/Waist circumferences. Conclusions These preliminary data on the first included participants of the COBRA-study do not shown an accelerated gain in fat mass and loss of muscle mass as induced during chemotherapy for women with breast cancer compared to women without breast cancer. Data on the full COBRA-study are expected in 2016.
Original languageEnglish
Publication statusPublished - 2014

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