Challenge models to study the effect of immune system activation on amino acid metabolism in pigs

E. van de Hoek; W.J.J. Gerrits; J.J.G.C. van den Borne; C.M.C. van der Peet-Schwering; H. van Beers; A.J.M. Jansman

doi:10.3920/978-90-8686-781-3_76

Challenge models to study the effect of immune system activation on amino acid metabolism in pigs

E. van de Hoek, W.J.J. Gerrits, J.J.G.C. van den Borne, C.M.C. van der Peet-Schwering, H. van Beers, A.J.M. Jansman

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › Academic › peer-review

Abstract

In response to (non-)pathogenic challenges, the immune system of pigs can be activated. During immune system activation, there is a competition for amino acids (AA) between body protein deposition (growth) and immune function (Sandberg et al., 2007). As a consequence, feed intake and growth are impaired (Williams et al., 1997) and body protein degradation increases to release AA, e.g. for the production of acute phase proteins (APP) (Reeds et al., 1994). Knowledge about the impact of immune system activation on AA metabolism of pigs is limited. The aim of the present study was to compare the use of Complete Freund’s Adjuvant (CFA) and turpentine oil (TO) to activate the immune system and to study the effect of immune system activation on AA metabolism in pigs.

Original language	English
Title of host publication	Proceedings of the 4th International Symposium on Energy and Protein Metabolism and Nutrition, 9-12 September 2013, Sacramento, California, USA
Editors	J.W. Oltjen, E. Kebreab, H. Lapierre
Place of Publication	Wageningen
Publisher	Wageningen Academic Publishers
Pages	237-238
Volume	134
ISBN (Print)	9789086862276
DOIs	https://doi.org/10.3920/978-90-8686-781-3_76
Publication status	Published - 2013
Event	4th International Symposium on Energy and Protein Metabolism and Nutrition, Sacramento, California, USA - Duration: 9 Sept 2013 → 12 Sept 2013

Conference

Conference	4th International Symposium on Energy and Protein Metabolism and Nutrition, Sacramento, California, USA
Period	9/09/13 → 12/09/13

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10.3920/978-90-8686-781-3_76

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van de Hoek, E., Gerrits, W. J. J., van den Borne, J. J. G. C., van der Peet-Schwering, C. M. C., van Beers, H., & Jansman, A. J. M. (2013). Challenge models to study the effect of immune system activation on amino acid metabolism in pigs. In J. W. Oltjen, E. Kebreab, & H. Lapierre (Eds.), Proceedings of the 4th International Symposium on Energy and Protein Metabolism and Nutrition, 9-12 September 2013, Sacramento, California, USA (Vol. 134, pp. 237-238). Wageningen Academic Publishers. https://doi.org/10.3920/978-90-8686-781-3_76

van de Hoek, E. ; Gerrits, W.J.J. ; van den Borne, J.J.G.C. et al. / Challenge models to study the effect of immune system activation on amino acid metabolism in pigs. Proceedings of the 4th International Symposium on Energy and Protein Metabolism and Nutrition, 9-12 September 2013, Sacramento, California, USA. editor / J.W. Oltjen ; E. Kebreab ; H. Lapierre. Vol. 134 Wageningen : Wageningen Academic Publishers, 2013. pp. 237-238

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title = "Challenge models to study the effect of immune system activation on amino acid metabolism in pigs",

abstract = "In response to (non-)pathogenic challenges, the immune system of pigs can be activated. During immune system activation, there is a competition for amino acids (AA) between body protein deposition (growth) and immune function (Sandberg et al., 2007). As a consequence, feed intake and growth are impaired (Williams et al., 1997) and body protein degradation increases to release AA, e.g. for the production of acute phase proteins (APP) (Reeds et al., 1994). Knowledge about the impact of immune system activation on AA metabolism of pigs is limited. The aim of the present study was to compare the use of Complete Freund{\textquoteright}s Adjuvant (CFA) and turpentine oil (TO) to activate the immune system and to study the effect of immune system activation on AA metabolism in pigs.",

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van de Hoek, E, Gerrits, WJJ, van den Borne, JJGC, van der Peet-Schwering, CMC, van Beers, H & Jansman, AJM 2013, Challenge models to study the effect of immune system activation on amino acid metabolism in pigs. in JW Oltjen, E Kebreab & H Lapierre (eds), Proceedings of the 4th International Symposium on Energy and Protein Metabolism and Nutrition, 9-12 September 2013, Sacramento, California, USA. vol. 134, Wageningen Academic Publishers, Wageningen, pp. 237-238, 4th International Symposium on Energy and Protein Metabolism and Nutrition, Sacramento, California, USA, 9/09/13. https://doi.org/10.3920/978-90-8686-781-3_76

Challenge models to study the effect of immune system activation on amino acid metabolism in pigs. / van de Hoek, E.; Gerrits, W.J.J.; van den Borne, J.J.G.C. et al.
Proceedings of the 4th International Symposium on Energy and Protein Metabolism and Nutrition, 9-12 September 2013, Sacramento, California, USA. ed. / J.W. Oltjen; E. Kebreab; H. Lapierre. Vol. 134 Wageningen: Wageningen Academic Publishers, 2013. p. 237-238.

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › Academic › peer-review

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AU - van de Hoek, E.

AU - Gerrits, W.J.J.

AU - van den Borne, J.J.G.C.

AU - van der Peet-Schwering, C.M.C.

AU - van Beers, H.

AU - Jansman, A.J.M.

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AB - In response to (non-)pathogenic challenges, the immune system of pigs can be activated. During immune system activation, there is a competition for amino acids (AA) between body protein deposition (growth) and immune function (Sandberg et al., 2007). As a consequence, feed intake and growth are impaired (Williams et al., 1997) and body protein degradation increases to release AA, e.g. for the production of acute phase proteins (APP) (Reeds et al., 1994). Knowledge about the impact of immune system activation on AA metabolism of pigs is limited. The aim of the present study was to compare the use of Complete Freund’s Adjuvant (CFA) and turpentine oil (TO) to activate the immune system and to study the effect of immune system activation on AA metabolism in pigs.

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BT - Proceedings of the 4th International Symposium on Energy and Protein Metabolism and Nutrition, 9-12 September 2013, Sacramento, California, USA

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van de Hoek E, Gerrits WJJ, van den Borne JJGC, van der Peet-Schwering CMC, van Beers H, Jansman AJM. Challenge models to study the effect of immune system activation on amino acid metabolism in pigs. In Oltjen JW, Kebreab E, Lapierre H, editors, Proceedings of the 4th International Symposium on Energy and Protein Metabolism and Nutrition, 9-12 September 2013, Sacramento, California, USA. Vol. 134. Wageningen: Wageningen Academic Publishers. 2013. p. 237-238 doi: 10.3920/978-90-8686-781-3_76

Challenge models to study the effect of immune system activation on amino acid metabolism in pigs

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