Cellular RNA Hubs: Friends and Foes of Plant Viruses

Min Xu, Magdalena J. Mazur, Xiaorong Tao, Richard Kormelink

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

RNA granules are dynamic cellular foci that are widely spread in eukaryotic cells and play essential roles in cell growth and development, and immune and stress responses. Different types of granules can be distinguished, each with a specific function and playing a role in, for example, RNA transcription, modification, processing, decay, translation, and arrest. By means of communication and exchange of (shared) components, they form a large regulatory network in cells. Viruses have been reported to interact with one or more of these either cytoplasmic or nuclear granules, and act either proviral, to enable and support viral infection and facilitate viral movement, or antiviral, protecting or clearing hosts from viral infection. This review describes an overview and recent progress on cytoplasmic and nuclear RNA granules and their interplay with virus infection, first in animal systems and as a prelude to the status and current developments on plant viruses, which have been less well studied on this thus far.
Original languageEnglish
Article numberMPMI-06-19-0161
JournalMolecular Plant-Microbe Interactions
Volume33
Issue number1
Early online date11 Nov 2019
DOIs
Publication statusPublished - Jan 2020

Fingerprint

Plant Viruses
plant viruses
Virus Diseases
granules
RNA
Nuclear RNA
Eukaryotic Cells
infection
Growth and Development
viruses
Antiviral Agents
Communication
animal communication
translation (genetics)
Viruses
eukaryotic cells
cell growth
stress response
growth and development
transcription (genetics)

Cite this

Xu, Min ; Mazur, Magdalena J. ; Tao, Xiaorong ; Kormelink, Richard. / Cellular RNA Hubs: Friends and Foes of Plant Viruses. In: Molecular Plant-Microbe Interactions. 2020 ; Vol. 33, No. 1.
@article{b55e5ae5874b42b697ee9780b8b6a907,
title = "Cellular RNA Hubs: Friends and Foes of Plant Viruses",
abstract = "RNA granules are dynamic cellular foci that are widely spread in eukaryotic cells and play essential roles in cell growth and development, and immune and stress responses. Different types of granules can be distinguished, each with a specific function and playing a role in, for example, RNA transcription, modification, processing, decay, translation, and arrest. By means of communication and exchange of (shared) components, they form a large regulatory network in cells. Viruses have been reported to interact with one or more of these either cytoplasmic or nuclear granules, and act either proviral, to enable and support viral infection and facilitate viral movement, or antiviral, protecting or clearing hosts from viral infection. This review describes an overview and recent progress on cytoplasmic and nuclear RNA granules and their interplay with virus infection, first in animal systems and as a prelude to the status and current developments on plant viruses, which have been less well studied on this thus far.",
author = "Min Xu and Mazur, {Magdalena J.} and Xiaorong Tao and Richard Kormelink",
year = "2020",
month = "1",
doi = "10.1094/MPMI-06-19-0161-FI",
language = "English",
volume = "33",
journal = "Molecular Plant-Microbe Interactions",
issn = "0894-0282",
publisher = "American Phytopathological Society",
number = "1",

}

Cellular RNA Hubs: Friends and Foes of Plant Viruses. / Xu, Min; Mazur, Magdalena J.; Tao, Xiaorong; Kormelink, Richard.

In: Molecular Plant-Microbe Interactions, Vol. 33, No. 1, MPMI-06-19-0161, 01.2020.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Cellular RNA Hubs: Friends and Foes of Plant Viruses

AU - Xu, Min

AU - Mazur, Magdalena J.

AU - Tao, Xiaorong

AU - Kormelink, Richard

PY - 2020/1

Y1 - 2020/1

N2 - RNA granules are dynamic cellular foci that are widely spread in eukaryotic cells and play essential roles in cell growth and development, and immune and stress responses. Different types of granules can be distinguished, each with a specific function and playing a role in, for example, RNA transcription, modification, processing, decay, translation, and arrest. By means of communication and exchange of (shared) components, they form a large regulatory network in cells. Viruses have been reported to interact with one or more of these either cytoplasmic or nuclear granules, and act either proviral, to enable and support viral infection and facilitate viral movement, or antiviral, protecting or clearing hosts from viral infection. This review describes an overview and recent progress on cytoplasmic and nuclear RNA granules and their interplay with virus infection, first in animal systems and as a prelude to the status and current developments on plant viruses, which have been less well studied on this thus far.

AB - RNA granules are dynamic cellular foci that are widely spread in eukaryotic cells and play essential roles in cell growth and development, and immune and stress responses. Different types of granules can be distinguished, each with a specific function and playing a role in, for example, RNA transcription, modification, processing, decay, translation, and arrest. By means of communication and exchange of (shared) components, they form a large regulatory network in cells. Viruses have been reported to interact with one or more of these either cytoplasmic or nuclear granules, and act either proviral, to enable and support viral infection and facilitate viral movement, or antiviral, protecting or clearing hosts from viral infection. This review describes an overview and recent progress on cytoplasmic and nuclear RNA granules and their interplay with virus infection, first in animal systems and as a prelude to the status and current developments on plant viruses, which have been less well studied on this thus far.

U2 - 10.1094/MPMI-06-19-0161-FI

DO - 10.1094/MPMI-06-19-0161-FI

M3 - Article

VL - 33

JO - Molecular Plant-Microbe Interactions

JF - Molecular Plant-Microbe Interactions

SN - 0894-0282

IS - 1

M1 - MPMI-06-19-0161

ER -