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Cas12a nickases

  • John van der Oost (Inventor)
  • , Ricardo Villegas Warren (Inventor)
  • , Maartje Janneke Luteijn (Inventor)
  • , Raymond Hubert Josèphe Staals (Inventor)
  • , Wen Ying Wu (Inventor)
  • , David De Vleesschauwer (Inventor)
  • , Katelijn D'Halluin (Inventor)
  • , Frank Meulewaeter (Inventor)

Research output: Patent

Abstract

The present invention relates to the field of gene genome editing. In particular, it relates to the provision of a Cas12a enzyme having nickase activity, as well as the means and methods for the modification of a genomic locus of interest with a Cas12a enzyme having nickase activity and uses thereof

Original languageEnglish
Patent numberWO2023166032
Priority date18/10/22
Publication statusPublished - 7 Sept 2023

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