Cas12a nickases

John van der Oost (Inventor), Ricardo Villegas Warren (Inventor), Maartje Janneke Luteijn (Inventor), Raymond Hubert Josèphe Staals (Inventor), Wen Ying Wu (Inventor), David De Vleesschauwer (Inventor), Katelijn D'Halluin (Inventor), Frank Meulewaeter (Inventor)

Research output: Patent

Abstract

The present invention relates to the field of gene genome editing. In particular, it relates to the provision of a Cas12a enzyme having nickase activity, as well as the means and methods for the modification of a genomic locus of interest with a Cas12a enzyme having nickase activity and uses thereof

Original languageEnglish
Patent numberWO2023166029
Priority date18/10/22
Publication statusPublished - 7 Sept 2023

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