Can recombinant milk proteins replace those produced by animals?

Kasper Hettinga*, Etske Bijl

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


The consumption of animal proteins in general, and dairy proteins in particular, is associated with sustainability and animal welfare issues. Recombinant synthesis of milk proteins is therefore receiving increasing interest, with several studies showing synthesis of milk proteins using a wide range of expression systems. Achieving a high yield and purity is essential for economic production. Besides the synthesis, also the construction of the specific structure in which milk proteins are present in animal milks, casein micelles, is needed. Looking at the current state-of-the-art, the steps to produce recombinant dairy products are technically feasible, but whether it can be implemented at low cost, with the process being environmentally friendly, remains to be seen in the coming years.

Original languageEnglish
Article number102690
JournalCurrent Opinion in Biotechnology
Publication statusPublished - Jun 2022


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