Breeding for healthier wheat

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

In this article wheat is described in its historical context, as a part of the Paleolithic diet and Neolithic “food package.” The health-promoting roles of wheat in the prevention of modern chronic diseases are described, as well as several wheat-related disorders. Celiac disease has particularly high negative economic and health effects. Several breeding strategies aimed at the reduction or elimination of celiac disease immunogenicity in wheat, such as selection, reconstitution, chemical- and irradiation-induced mutation, and the application of advanced techniques (including genetic modification and CRISPR-Cas9 [clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9]), have been elaborated and evaluated.
Original languageEnglish
Pages (from-to)132-136
JournalCereal Foods World
Volume63
Issue number4
DOIs
Publication statusPublished - 1 Jul 2018

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Triticum
Breeding
wheat
celiac disease
breeding
Celiac Disease
CRISPR-Associated Proteins
Clustered Regularly Interspaced Short Palindromic Repeats
Genetic Techniques
health promotion
Health
chronic diseases
genetic engineering
mutagenesis
Chronic Disease
irradiation
Economics
immune response
Food
economics

Cite this

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title = "Breeding for healthier wheat",
abstract = "In this article wheat is described in its historical context, as a part of the Paleolithic diet and Neolithic “food package.” The health-promoting roles of wheat in the prevention of modern chronic diseases are described, as well as several wheat-related disorders. Celiac disease has particularly high negative economic and health effects. Several breeding strategies aimed at the reduction or elimination of celiac disease immunogenicity in wheat, such as selection, reconstitution, chemical- and irradiation-induced mutation, and the application of advanced techniques (including genetic modification and CRISPR-Cas9 [clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9]), have been elaborated and evaluated.",
author = "Gilissen, {Luud J.W.J.} and {van den Broeck}, {Hetty C.}",
year = "2018",
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doi = "10.1094/CFW-63-4-0132",
language = "English",
volume = "63",
pages = "132--136",
journal = "Cereal Foods World",
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publisher = "American Association of Cereal Chemists",
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}

Breeding for healthier wheat. / Gilissen, Luud J.W.J.; van den Broeck, Hetty C.

In: Cereal Foods World, Vol. 63, No. 4, 01.07.2018, p. 132-136.

Research output: Contribution to journalReview articleAcademicpeer-review

TY - JOUR

T1 - Breeding for healthier wheat

AU - Gilissen, Luud J.W.J.

AU - van den Broeck, Hetty C.

PY - 2018/7/1

Y1 - 2018/7/1

N2 - In this article wheat is described in its historical context, as a part of the Paleolithic diet and Neolithic “food package.” The health-promoting roles of wheat in the prevention of modern chronic diseases are described, as well as several wheat-related disorders. Celiac disease has particularly high negative economic and health effects. Several breeding strategies aimed at the reduction or elimination of celiac disease immunogenicity in wheat, such as selection, reconstitution, chemical- and irradiation-induced mutation, and the application of advanced techniques (including genetic modification and CRISPR-Cas9 [clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9]), have been elaborated and evaluated.

AB - In this article wheat is described in its historical context, as a part of the Paleolithic diet and Neolithic “food package.” The health-promoting roles of wheat in the prevention of modern chronic diseases are described, as well as several wheat-related disorders. Celiac disease has particularly high negative economic and health effects. Several breeding strategies aimed at the reduction or elimination of celiac disease immunogenicity in wheat, such as selection, reconstitution, chemical- and irradiation-induced mutation, and the application of advanced techniques (including genetic modification and CRISPR-Cas9 [clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9]), have been elaborated and evaluated.

U2 - 10.1094/CFW-63-4-0132

DO - 10.1094/CFW-63-4-0132

M3 - Review article

VL - 63

SP - 132

EP - 136

JO - Cereal Foods World

JF - Cereal Foods World

SN - 0146-6283

IS - 4

ER -