Biosynthesis of raspberry ketone

M.J. Beekwilder (Inventor), O. Sibbensen (Inventor), J.D. Mikkelsen (Inventor), I.M. van der Meer (Inventor), R.D. Hall (Inventor), I. Qvist (Inventor)

Research output: PatentOther research output

Abstract

A host cell comprising a benzalacetone synthase (BAS) polypeptide sequence and a 4-coumarate:CoA ligase (4CL) sequence in which one or both of the BAS polypeptide sequence and the 4CL sequence is heterologous to the host cell. Such a host cell is useful in the production of benzalacetone and/or raspberry ketone from precursors such as p-coumaric acid. Also claimed is a method of producing raspberry ketone comprising supplying a bacteria with benzalacetone.
Original languageEnglish
Patent numberGB2416769
Publication statusPublished - 8 Feb 2006

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Peptides
Bacteria
raspberry ketone
benzylideneacetone
4-coumarate-CoA ligase
4-coumaric acid

Cite this

Beekwilder, M. J., Sibbensen, O., Mikkelsen, J. D., van der Meer, I. M., Hall, R. D., & Qvist, I. (2006). Biosynthesis of raspberry ketone. (Patent No. GB2416769).
Beekwilder, M.J. (Inventor) ; Sibbensen, O. (Inventor) ; Mikkelsen, J.D. (Inventor) ; van der Meer, I.M. (Inventor) ; Hall, R.D. (Inventor) ; Qvist, I. (Inventor). / Biosynthesis of raspberry ketone. Patent No.: GB2416769.
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title = "Biosynthesis of raspberry ketone",
abstract = "A host cell comprising a benzalacetone synthase (BAS) polypeptide sequence and a 4-coumarate:CoA ligase (4CL) sequence in which one or both of the BAS polypeptide sequence and the 4CL sequence is heterologous to the host cell. Such a host cell is useful in the production of benzalacetone and/or raspberry ketone from precursors such as p-coumaric acid. Also claimed is a method of producing raspberry ketone comprising supplying a bacteria with benzalacetone.",
author = "M.J. Beekwilder and O. Sibbensen and J.D. Mikkelsen and {van der Meer}, I.M. and R.D. Hall and I. Qvist",
year = "2006",
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day = "8",
language = "English",
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note = "GB2416769",

}

Beekwilder, MJ, Sibbensen, O, Mikkelsen, JD, van der Meer, IM, Hall, RD & Qvist, I 2006, Biosynthesis of raspberry ketone, Patent No. GB2416769.

Biosynthesis of raspberry ketone. / Beekwilder, M.J. (Inventor); Sibbensen, O. (Inventor); Mikkelsen, J.D. (Inventor); van der Meer, I.M. (Inventor); Hall, R.D. (Inventor); Qvist, I. (Inventor).

Patent No.: GB2416769.

Research output: PatentOther research output

TY - PAT

T1 - Biosynthesis of raspberry ketone

AU - Beekwilder, M.J.

AU - Sibbensen, O.

AU - Mikkelsen, J.D.

AU - van der Meer, I.M.

AU - Hall, R.D.

AU - Qvist, I.

PY - 2006/2/8

Y1 - 2006/2/8

N2 - A host cell comprising a benzalacetone synthase (BAS) polypeptide sequence and a 4-coumarate:CoA ligase (4CL) sequence in which one or both of the BAS polypeptide sequence and the 4CL sequence is heterologous to the host cell. Such a host cell is useful in the production of benzalacetone and/or raspberry ketone from precursors such as p-coumaric acid. Also claimed is a method of producing raspberry ketone comprising supplying a bacteria with benzalacetone.

AB - A host cell comprising a benzalacetone synthase (BAS) polypeptide sequence and a 4-coumarate:CoA ligase (4CL) sequence in which one or both of the BAS polypeptide sequence and the 4CL sequence is heterologous to the host cell. Such a host cell is useful in the production of benzalacetone and/or raspberry ketone from precursors such as p-coumaric acid. Also claimed is a method of producing raspberry ketone comprising supplying a bacteria with benzalacetone.

M3 - Patent

M1 - GB2416769

ER -

Beekwilder MJ, Sibbensen O, Mikkelsen JD, van der Meer IM, Hall RD, Qvist I, inventors. Biosynthesis of raspberry ketone. GB2416769. 2006 Feb 8.