A host cell comprising a benzalacetone synthase (BAS) polypeptide sequence and a 4-coumarate:CoA ligase (4CL) sequence in which one or both of the BAS polypeptide sequence and the 4CL sequence is heterologous to the host cell. Such a host cell is useful in the production of benzalacetone and/or raspberry ketone from precursors such as p-coumaric acid. Also claimed is a method of producing raspberry ketone comprising supplying a bacteria with benzalacetone.
|Publication status||Published - 8 Feb 2006|
Beekwilder, M. J., Sibbensen, O., Mikkelsen, J. D., van der Meer, I. M., Hall, R. D., & Qvist, I. (2006). Biosynthesis of raspberry ketone. (Patent No. GB2416769). https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=GB&NR=2416769A&KC=A&FT=D&ND=3&date=20060208&DB=&locale=en_EP#