BIOCLAIMS standard diet (BIOsd): a reference diet for nutritional physiology

F.P.M. Hoevenaars, E.M. van Schothorst, O. Horakova, A. Voigt, M. Rossmeisl, C. Pico, A. Caimari, J. Kopecky, S. Klaus, J. Keijer

Research output: Contribution to journalArticleAcademicpeer-review

28 Citations (Scopus)

Abstract

Experimental replication is fundamental for practicing science. To reduce variability, it is essential to control sources of variation as much as possible. Diet is an important factor that can influence many processes and functional outcomes in studies performed with rodent models. This is especially true for, but not limited to, nutritional studies. To compare functional effects of different nutrients, it is important to use standardized, semi-purified diets. Here, we propose and describe a standard reference diet, the BIOCLAIMS standard diet. The diet is AIN-93 based, but further defined with dietary and experimental requirements taken into account that allow for experiments with bioactive food components and natural (non-expensive) labeling. This diet will be implemented by two European research consortia, Mitofood and BIOCLAIMS, to ensure inter-laboratory comparability.
Original languageEnglish
Pages (from-to)399-404
JournalGenes & Nutrition
Volume7
Issue number3
DOIs
Publication statusPublished - 2012

Keywords

  • laboratory-animal diets
  • gene-expression
  • fat oxidation
  • mice
  • energy
  • rats
  • metabolism

Fingerprint Dive into the research topics of 'BIOCLAIMS standard diet (BIOsd): a reference diet for nutritional physiology'. Together they form a unique fingerprint.

  • Cite this