Bioavailability, antioxidant and biological properties of the natural free-radical scavengers cyanidin and related glycosides

Fabio Galvano*, Luca La Fauci, Paola Vitaglione, Vincenzo Fogliano, Luca Vanella, Catherine Felgines

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

88 Citations (Scopus)

Abstract

Cyanidin and its glycosides (Cy and Cyg) have been indicated as promising candidates as dietary compounds with a potential role in human health. They are the largest class of water-soluble compounds in plants, where they are responsible for the brillant color (red, orange, blue) of fruits and flowers. As natural compounds of several foods such as vegetables, fruits and red wines, they are estimated to be widely ingested by humans. This paper, basing on the data previously reviewed in 2002, focuses on the findings regarding human and animal studies on Cy and Cyg absorption and metabolism, antioxidant activity and biological properties, with particular attention to anticarcinogenic activity, vasoprotective, anti-inflammatory, anti-obesity and anti-diabetes effects. It is concluded that although Cy and Cyg bioavailability is low, further investigations are necessary because some important metabolites may still not have been identified. Literature data on antioxidant activity and biological properties, however, widely confirm Cy and Cyg as dietary compounds with a potential beneficial role in human health.

Original languageEnglish
Pages (from-to)382-393
Number of pages12
JournalAnnali dell'Istituto Superiore di Sanita
Volume43
Issue number4
Publication statusPublished - 2007
Externally publishedYes

Keywords

  • Antioxidant activity
  • Biological properties
  • Cyanidin
  • Cyanidin glycosides

Fingerprint Dive into the research topics of 'Bioavailability, antioxidant and biological properties of the natural free-radical scavengers cyanidin and related glycosides'. Together they form a unique fingerprint.

Cite this