Bias and random error in retinol measurements of laboratories in countries with populations with mild to severe vitamin A deficiency

P.J.M. Hulshof, J.T. Brouwer, J. Burema, C.E. West

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Abstract

Vitamin A deficiency is common in many developing countries. Population-based surveys suggest that as many as 175 million children of preschool age are vitamin A-deficient (1). Especially in sub-Saharan Africa, severe subclinical deficiency (retinol values 0.70 µmol/L) often exceeds 30%. In these countries, laboratories should be able to measure the biochemical indicators of nutritional status to acceptable standards. The aim of the present study was to determine the proficiency of selected laboratories, particularly in Africa, in measuring retinol in serum
Original languageEnglish
Pages (from-to)2061-2063
JournalClinical Chemistry
Volume48
Issue number11
Publication statusPublished - 2002

Keywords

  • performance
  • chromatography
  • carotenoids

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