The INNOVATE project, a comprehensive Brazilian-German research collaboration, addresses sustainable land management in the São Francisco watershed and its Itaparica reservoir. The project studies management options, which promote sustainable ecosystem services and economic viability in climate change conditions. At basin scale, questions of water quantity and quality prevail, including resource allocation and governance. Local and regional studies investigate natural land processes and water resources in addition to their management post dam construction. Consortium researchers are confronted with a multitude of expectations, ranging from knowledge production to interacting with stakeholders and scientists of different disciplines and cultures. As an overview, we predicted potential changes of studied ecosystem services under different conditions within possible scenarios. Further integration of results is ongoing, as is the conversion of scientific results into guidance for stakeholders.