Bacteria-comprising compositions and methods of using the same for treating and/or preventing gastrointestinal, metabolic and/or other diseases

W.M. de Vos

Bacteria-comprising compositions and methods of using the same for treating and/or preventing gastrointestinal, metabolic and/or other diseases

Research output: Patent › Other research output

Abstract

The invention is concerned with a novel human intestinal isolate capable of converting L- lysine into butyrate and/or of converting fructose-lysine into butyrate. The novel isolate can be used as a probiotic or supplement to promote production of butyrate in the Gl tract, thereby preventing and/or treating conditions or diseases that benefit from the production of butyrate. Additionally, the isolate may prevent and/or treat conditions or diseases caused by an excess of pathogenic bacteria in the Gl tract, mediated by L-lysine, or mediated by fructose-lysine or other advanced glycation end products.

Original language	English
Patent number	WO2016110585
Priority date	9/01/15
Publication status	Published - 14 Jul 2016

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https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=WO&NR=2016110585A1&KC=A1&FT=D&ND=3&date=20160714&DB=EPODOC&locale=en_EP

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title = "Bacteria-comprising compositions and methods of using the same for treating and/or preventing gastrointestinal, metabolic and/or other diseases",

abstract = "The invention is concerned with a novel human intestinal isolate capable of converting L- lysine into butyrate and/or of converting fructose-lysine into butyrate. The novel isolate can be used as a probiotic or supplement to promote production of butyrate in the Gl tract, thereby preventing and/or treating conditions or diseases that benefit from the production of butyrate. Additionally, the isolate may prevent and/or treat conditions or diseases caused by an excess of pathogenic bacteria in the Gl tract, mediated by L-lysine, or mediated by fructose-lysine or other advanced glycation end products.",

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N2 - The invention is concerned with a novel human intestinal isolate capable of converting L- lysine into butyrate and/or of converting fructose-lysine into butyrate. The novel isolate can be used as a probiotic or supplement to promote production of butyrate in the Gl tract, thereby preventing and/or treating conditions or diseases that benefit from the production of butyrate. Additionally, the isolate may prevent and/or treat conditions or diseases caused by an excess of pathogenic bacteria in the Gl tract, mediated by L-lysine, or mediated by fructose-lysine or other advanced glycation end products.

AB - The invention is concerned with a novel human intestinal isolate capable of converting L- lysine into butyrate and/or of converting fructose-lysine into butyrate. The novel isolate can be used as a probiotic or supplement to promote production of butyrate in the Gl tract, thereby preventing and/or treating conditions or diseases that benefit from the production of butyrate. Additionally, the isolate may prevent and/or treat conditions or diseases caused by an excess of pathogenic bacteria in the Gl tract, mediated by L-lysine, or mediated by fructose-lysine or other advanced glycation end products.

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