The invention relates to bacterial infections, vaccines directed against those infections and bacterial vaccines. More particularly, the invention relates to vaccines directed against Streptococcus infections in pigs. Provided is a ΔFolT mutant of a bacterium having reduced capacity to transport folate, wherein the capacity has been reduced by functionally deleting folate transporter (FolT) function. Also provided is a method to reduce virulence of a bacterium comprising reducing the capacity of the bacterium to transport folate.
|Publication status||Published - 17 May 2018|