Association of long-term adherence to the mind diet with cognitive function and cognitive decline in American women

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Abstract

Objectives: There is increasing attention for dietary patterns as a potential strategy to prevent cognitive decline. We examined the association between adherence to a recently developed Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet with cognitive function and cognitive decline, taking into account the interaction between the apolipoprotein E ε4 genotype and the MIND diet. Design: Population-based prospective cohort study. Participants: A total of 16,058 older women aged 70 and over from the Nurses’ Health Study. Measurements: Dietary intake was assessed five times between 1984 and 1998 with a 116-item Food Frequency Questionnaire. The MIND score includes ten brain-healthy foods and five unhealthy foods. Cognition was assessed four times by telephone from 1995 to 2001 (baseline) with the Telephone Interview for Cognitive Status (TICS) and by calculating composite scores of verbal memory and global cognition. Linear regression modelling and linear mixed modelling were used to examine the associations of adherence to the MIND diet with average cognitive function and cognitive change over six years, respectively. Results: Greater long-term adherence to the MIND diet was associated with a better verbal memory score (multivariable-adjusted mean differences between extreme MIND quintiles=0.04 (95%CI 0.01-0.07), p-trend=0.006), but not with cognitive decline over 6 years in global cognition, verbal memory or TICS. Conclusion: Long-term adherence to the MIND diet was moderately associated with better verbal memory in later life. Future studies should address this association within populations at greater risk of cognitive decline.

Original languageEnglish
Pages (from-to)222-229
JournalJournal of Nutrition, Health and Aging
Volume22
Issue number2
Early online date23 Mar 2017
DOIs
Publication statusPublished - Feb 2018

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Cognition
Diet
Food
Interviews
Apolipoprotein E4
Telephone
Linear Models
Cohort Studies
Nurses
Genotype
Cognitive Dysfunction
Prospective Studies
Health
Brain
Population

Cite this

@article{1b28e7936a51452687f1d583e200a5ad,
title = "Association of long-term adherence to the mind diet with cognitive function and cognitive decline in American women",
abstract = "Objectives: There is increasing attention for dietary patterns as a potential strategy to prevent cognitive decline. We examined the association between adherence to a recently developed Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet with cognitive function and cognitive decline, taking into account the interaction between the apolipoprotein E ε4 genotype and the MIND diet. Design: Population-based prospective cohort study. Participants: A total of 16,058 older women aged 70 and over from the Nurses’ Health Study. Measurements: Dietary intake was assessed five times between 1984 and 1998 with a 116-item Food Frequency Questionnaire. The MIND score includes ten brain-healthy foods and five unhealthy foods. Cognition was assessed four times by telephone from 1995 to 2001 (baseline) with the Telephone Interview for Cognitive Status (TICS) and by calculating composite scores of verbal memory and global cognition. Linear regression modelling and linear mixed modelling were used to examine the associations of adherence to the MIND diet with average cognitive function and cognitive change over six years, respectively. Results: Greater long-term adherence to the MIND diet was associated with a better verbal memory score (multivariable-adjusted mean differences between extreme MIND quintiles=0.04 (95{\%}CI 0.01-0.07), p-trend=0.006), but not with cognitive decline over 6 years in global cognition, verbal memory or TICS. Conclusion: Long-term adherence to the MIND diet was moderately associated with better verbal memory in later life. Future studies should address this association within populations at greater risk of cognitive decline.",
author = "Agnes Berendsen and J.H. Kang and E.J.M. Feskens and {de Groot}, C.P.G.M. and F. Grodstein and {van de Rest}, O.",
year = "2018",
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language = "English",
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pages = "222--229",
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Association of long-term adherence to the mind diet with cognitive function and cognitive decline in American women. / Berendsen, Agnes; Kang, J.H.; Feskens, E.J.M.; de Groot, C.P.G.M.; Grodstein, F.; van de Rest, O.

In: Journal of Nutrition, Health and Aging, Vol. 22, No. 2, 02.2018, p. 222-229.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Association of long-term adherence to the mind diet with cognitive function and cognitive decline in American women

AU - Berendsen, Agnes

AU - Kang, J.H.

AU - Feskens, E.J.M.

AU - de Groot, C.P.G.M.

AU - Grodstein, F.

AU - van de Rest, O.

PY - 2018/2

Y1 - 2018/2

N2 - Objectives: There is increasing attention for dietary patterns as a potential strategy to prevent cognitive decline. We examined the association between adherence to a recently developed Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet with cognitive function and cognitive decline, taking into account the interaction between the apolipoprotein E ε4 genotype and the MIND diet. Design: Population-based prospective cohort study. Participants: A total of 16,058 older women aged 70 and over from the Nurses’ Health Study. Measurements: Dietary intake was assessed five times between 1984 and 1998 with a 116-item Food Frequency Questionnaire. The MIND score includes ten brain-healthy foods and five unhealthy foods. Cognition was assessed four times by telephone from 1995 to 2001 (baseline) with the Telephone Interview for Cognitive Status (TICS) and by calculating composite scores of verbal memory and global cognition. Linear regression modelling and linear mixed modelling were used to examine the associations of adherence to the MIND diet with average cognitive function and cognitive change over six years, respectively. Results: Greater long-term adherence to the MIND diet was associated with a better verbal memory score (multivariable-adjusted mean differences between extreme MIND quintiles=0.04 (95%CI 0.01-0.07), p-trend=0.006), but not with cognitive decline over 6 years in global cognition, verbal memory or TICS. Conclusion: Long-term adherence to the MIND diet was moderately associated with better verbal memory in later life. Future studies should address this association within populations at greater risk of cognitive decline.

AB - Objectives: There is increasing attention for dietary patterns as a potential strategy to prevent cognitive decline. We examined the association between adherence to a recently developed Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet with cognitive function and cognitive decline, taking into account the interaction between the apolipoprotein E ε4 genotype and the MIND diet. Design: Population-based prospective cohort study. Participants: A total of 16,058 older women aged 70 and over from the Nurses’ Health Study. Measurements: Dietary intake was assessed five times between 1984 and 1998 with a 116-item Food Frequency Questionnaire. The MIND score includes ten brain-healthy foods and five unhealthy foods. Cognition was assessed four times by telephone from 1995 to 2001 (baseline) with the Telephone Interview for Cognitive Status (TICS) and by calculating composite scores of verbal memory and global cognition. Linear regression modelling and linear mixed modelling were used to examine the associations of adherence to the MIND diet with average cognitive function and cognitive change over six years, respectively. Results: Greater long-term adherence to the MIND diet was associated with a better verbal memory score (multivariable-adjusted mean differences between extreme MIND quintiles=0.04 (95%CI 0.01-0.07), p-trend=0.006), but not with cognitive decline over 6 years in global cognition, verbal memory or TICS. Conclusion: Long-term adherence to the MIND diet was moderately associated with better verbal memory in later life. Future studies should address this association within populations at greater risk of cognitive decline.

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JO - Journal of Nutrition, Health and Aging

JF - Journal of Nutrition, Health and Aging

SN - 1279-7707

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ER -