Assessing the efficacy of vaccination strategies in curbing epidemics of Foot-and-Mouth Disease in The Netherlands.

    Research output: Contribution to conferencePaperAcademic

    Abstract

    The 2001 epidemic of Foot- and Mouth Disease (FMD) in the Netherlands has been brought to a halt by a combination of pre-emptive culling, emergency vaccination and depopulation measures in a large area comprising about 1800 farms. After the large Dutch HPAI epidemic in poultry in 2003, public acceptance of intervention strategies based on massive culling has further eroded. Policy makers in the Netherlands are therefore interested in assessing the use of emergency vaccination as a basis for intervention in the future. Here we use spatial transmission models to analyse the transmission potential of FMD between farms in the Netherlands, and to assess the expected efficacy of a set of alternative emergency vaccination strategies in curbing FMD spread. Our results, presented in the form of risk-maps for FMD spread, suggest that ring-culling or ring-vaccination strategies are insufficiently effective to achieve epidemic control in certain important areas in the Netherlands (with high densities of farms). In these areas only area-wide culling and/or vaccination strategies would stand a chance of being effective. On the positive side, our results suggest that in much of the Netherlands outside the high-density areas, standard intervention measures as required by the EU (a movement standstill, bio-security measures and culling of infected farms and dangerous-contact farms) would be sufficient to curb local propagation of the epidemic

    Conference

    Conference11th Symposium of the International Society for Veterinary Epidemiology and Economics
    Period6/08/0611/08/06

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    foot-and-mouth disease
    Netherlands
    vaccination
    farms
    biosecurity
    poultry

    Cite this

    @conference{4f1fc8afb1ef4fc99264c3dfe677d3cb,
    title = "Assessing the efficacy of vaccination strategies in curbing epidemics of Foot-and-Mouth Disease in The Netherlands.",
    abstract = "The 2001 epidemic of Foot- and Mouth Disease (FMD) in the Netherlands has been brought to a halt by a combination of pre-emptive culling, emergency vaccination and depopulation measures in a large area comprising about 1800 farms. After the large Dutch HPAI epidemic in poultry in 2003, public acceptance of intervention strategies based on massive culling has further eroded. Policy makers in the Netherlands are therefore interested in assessing the use of emergency vaccination as a basis for intervention in the future. Here we use spatial transmission models to analyse the transmission potential of FMD between farms in the Netherlands, and to assess the expected efficacy of a set of alternative emergency vaccination strategies in curbing FMD spread. Our results, presented in the form of risk-maps for FMD spread, suggest that ring-culling or ring-vaccination strategies are insufficiently effective to achieve epidemic control in certain important areas in the Netherlands (with high densities of farms). In these areas only area-wide culling and/or vaccination strategies would stand a chance of being effective. On the positive side, our results suggest that in much of the Netherlands outside the high-density areas, standard intervention measures as required by the EU (a movement standstill, bio-security measures and culling of infected farms and dangerous-contact farms) would be sufficient to curb local propagation of the epidemic",
    author = "G.J. Boender and T.H.J. Hagenaars and {van Roermund}, H.J.W. and {de Jong}, M.C.M.",
    year = "2006",
    language = "English",
    note = "11th Symposium of the International Society for Veterinary Epidemiology and Economics ; Conference date: 06-08-2006 Through 11-08-2006",

    }

    Boender, GJ, Hagenaars, THJ, van Roermund, HJW & de Jong, MCM 2006, 'Assessing the efficacy of vaccination strategies in curbing epidemics of Foot-and-Mouth Disease in The Netherlands.' Paper presented at 11th Symposium of the International Society for Veterinary Epidemiology and Economics, 6/08/06 - 11/08/06, .

    Assessing the efficacy of vaccination strategies in curbing epidemics of Foot-and-Mouth Disease in The Netherlands. / Boender, G.J.; Hagenaars, T.H.J.; van Roermund, H.J.W.; de Jong, M.C.M.

    2006. Paper presented at 11th Symposium of the International Society for Veterinary Epidemiology and Economics, .

    Research output: Contribution to conferencePaperAcademic

    TY - CONF

    T1 - Assessing the efficacy of vaccination strategies in curbing epidemics of Foot-and-Mouth Disease in The Netherlands.

    AU - Boender, G.J.

    AU - Hagenaars, T.H.J.

    AU - van Roermund, H.J.W.

    AU - de Jong, M.C.M.

    PY - 2006

    Y1 - 2006

    N2 - The 2001 epidemic of Foot- and Mouth Disease (FMD) in the Netherlands has been brought to a halt by a combination of pre-emptive culling, emergency vaccination and depopulation measures in a large area comprising about 1800 farms. After the large Dutch HPAI epidemic in poultry in 2003, public acceptance of intervention strategies based on massive culling has further eroded. Policy makers in the Netherlands are therefore interested in assessing the use of emergency vaccination as a basis for intervention in the future. Here we use spatial transmission models to analyse the transmission potential of FMD between farms in the Netherlands, and to assess the expected efficacy of a set of alternative emergency vaccination strategies in curbing FMD spread. Our results, presented in the form of risk-maps for FMD spread, suggest that ring-culling or ring-vaccination strategies are insufficiently effective to achieve epidemic control in certain important areas in the Netherlands (with high densities of farms). In these areas only area-wide culling and/or vaccination strategies would stand a chance of being effective. On the positive side, our results suggest that in much of the Netherlands outside the high-density areas, standard intervention measures as required by the EU (a movement standstill, bio-security measures and culling of infected farms and dangerous-contact farms) would be sufficient to curb local propagation of the epidemic

    AB - The 2001 epidemic of Foot- and Mouth Disease (FMD) in the Netherlands has been brought to a halt by a combination of pre-emptive culling, emergency vaccination and depopulation measures in a large area comprising about 1800 farms. After the large Dutch HPAI epidemic in poultry in 2003, public acceptance of intervention strategies based on massive culling has further eroded. Policy makers in the Netherlands are therefore interested in assessing the use of emergency vaccination as a basis for intervention in the future. Here we use spatial transmission models to analyse the transmission potential of FMD between farms in the Netherlands, and to assess the expected efficacy of a set of alternative emergency vaccination strategies in curbing FMD spread. Our results, presented in the form of risk-maps for FMD spread, suggest that ring-culling or ring-vaccination strategies are insufficiently effective to achieve epidemic control in certain important areas in the Netherlands (with high densities of farms). In these areas only area-wide culling and/or vaccination strategies would stand a chance of being effective. On the positive side, our results suggest that in much of the Netherlands outside the high-density areas, standard intervention measures as required by the EU (a movement standstill, bio-security measures and culling of infected farms and dangerous-contact farms) would be sufficient to curb local propagation of the epidemic

    M3 - Paper

    ER -

    Boender GJ, Hagenaars THJ, van Roermund HJW, de Jong MCM. Assessing the efficacy of vaccination strategies in curbing epidemics of Foot-and-Mouth Disease in The Netherlands.. 2006. Paper presented at 11th Symposium of the International Society for Veterinary Epidemiology and Economics, .