Aspergillus oryzae in solid-state and submerged fermentations. Progress report on a multi-disciplinary project

R. te Biesebeke; G. Ruijter; Y.S.P. Rahardjo; M.J. Hoogschagen; M. Heerikhuisen; A. Levin; K.G.A. van Driel; M.A.I. Schutyser; J. Dijksterhuis; Yang Yang Zhu; F.J. Weber; W.M. de Vos; K.A. van den Hondel; A. Rinzema; P.J. Punt

doi:10.1111/j.1567-1364.2002.tb00089.x

Aspergillus oryzae in solid-state and submerged fermentations. Progress report on a multi-disciplinary project

R. te Biesebeke, G. Ruijter, Y.S.P. Rahardjo, M.J. Hoogschagen, M. Heerikhuisen, A. Levin, K.G.A. van Driel, M.A.I. Schutyser, J. Dijksterhuis, Yang Yang Zhu, F.J. Weber, W.M. de Vos, K.A. van den Hondel, A. Rinzema, P.J. Punt

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Abstract

We report the progress of a multi-disciplinary research project on solid-state fermentation (SSF) of the filamentous fungus Aspergillus oryzae. The molecular and physiological aspects of the fungus in submerged fermentation (SmF) and SSF are compared and we observe a number of differences correlated with the different growth conditions. First, the aerial hyphae which occur only in SSFs are mainly responsible for oxygen uptake. Second, SSF is characterised by gradients in temperature, water activity and nutrient concentration, and inside the hyphae different polyols are accumulating. Third, pelleted growth in SmF and mycelial growth in SSF show different gene expression and protein secretion patterns. With this approach we aim to expand our knowledge of mechanisms of fungal growth on solid substrates and to exploit the biotechnological applications

Original language	English
Pages (from-to)	245-248
Journal	FEMS Yeast Research
Volume	2
Issue number	2
DOIs	https://doi.org/10.1111/j.1567-1364.2002.tb00089.x
Publication status	Published - 2002

Keywords

encoding gene glab
fungal growth
culture
expression
limitation
oxygen

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te Biesebeke, R., Ruijter, G., Rahardjo, Y. S. P., Hoogschagen, M. J., Heerikhuisen, M., Levin, A., van Driel, K. G. A., Schutyser, M. A. I., Dijksterhuis, J., Yang Zhu, Y., Weber, F. J., de Vos, W. M., van den Hondel, K. A., Rinzema, A., & Punt, P. J. (2002). Aspergillus oryzae in solid-state and submerged fermentations. Progress report on a multi-disciplinary project. FEMS Yeast Research, 2(2), 245-248. https://doi.org/10.1111/j.1567-1364.2002.tb00089.x

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title = "Aspergillus oryzae in solid-state and submerged fermentations. Progress report on a multi-disciplinary project",

abstract = "We report the progress of a multi-disciplinary research project on solid-state fermentation (SSF) of the filamentous fungus Aspergillus oryzae. The molecular and physiological aspects of the fungus in submerged fermentation (SmF) and SSF are compared and we observe a number of differences correlated with the different growth conditions. First, the aerial hyphae which occur only in SSFs are mainly responsible for oxygen uptake. Second, SSF is characterised by gradients in temperature, water activity and nutrient concentration, and inside the hyphae different polyols are accumulating. Third, pelleted growth in SmF and mycelial growth in SSF show different gene expression and protein secretion patterns. With this approach we aim to expand our knowledge of mechanisms of fungal growth on solid substrates and to exploit the biotechnological applications",

keywords = "encoding gene glab, fungal growth, culture, expression, limitation, oxygen",

author = "{te Biesebeke}, R. and G. Ruijter and Y.S.P. Rahardjo and M.J. Hoogschagen and M. Heerikhuisen and A. Levin and {van Driel}, K.G.A. and M.A.I. Schutyser and J. Dijksterhuis and {Yang Zhu}, Yang and F.J. Weber and {de Vos}, W.M. and {van den Hondel}, K.A. and A. Rinzema and P.J. Punt",

year = "2002",

doi = "10.1111/j.1567-1364.2002.tb00089.x",

language = "English",

volume = "2",

pages = "245--248",

journal = "FEMS Yeast Research",

issn = "1567-1356",

publisher = "Oxford University Press",

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te Biesebeke, R, Ruijter, G, Rahardjo, YSP, Hoogschagen, MJ, Heerikhuisen, M, Levin, A, van Driel, KGA, Schutyser, MAI, Dijksterhuis, J, Yang Zhu, Y, Weber, FJ, de Vos, WM, van den Hondel, KA, Rinzema, A & Punt, PJ 2002, 'Aspergillus oryzae in solid-state and submerged fermentations. Progress report on a multi-disciplinary project', FEMS Yeast Research, vol. 2, no. 2, pp. 245-248. https://doi.org/10.1111/j.1567-1364.2002.tb00089.x

TY - JOUR

T1 - Aspergillus oryzae in solid-state and submerged fermentations. Progress report on a multi-disciplinary project

AU - te Biesebeke, R.

AU - Ruijter, G.

AU - Rahardjo, Y.S.P.

AU - Hoogschagen, M.J.

AU - Heerikhuisen, M.

AU - Levin, A.

AU - van Driel, K.G.A.

AU - Schutyser, M.A.I.

AU - Dijksterhuis, J.

AU - Yang Zhu, Yang

AU - Weber, F.J.

AU - de Vos, W.M.

AU - van den Hondel, K.A.

AU - Rinzema, A.

AU - Punt, P.J.

PY - 2002

Y1 - 2002

N2 - We report the progress of a multi-disciplinary research project on solid-state fermentation (SSF) of the filamentous fungus Aspergillus oryzae. The molecular and physiological aspects of the fungus in submerged fermentation (SmF) and SSF are compared and we observe a number of differences correlated with the different growth conditions. First, the aerial hyphae which occur only in SSFs are mainly responsible for oxygen uptake. Second, SSF is characterised by gradients in temperature, water activity and nutrient concentration, and inside the hyphae different polyols are accumulating. Third, pelleted growth in SmF and mycelial growth in SSF show different gene expression and protein secretion patterns. With this approach we aim to expand our knowledge of mechanisms of fungal growth on solid substrates and to exploit the biotechnological applications

AB - We report the progress of a multi-disciplinary research project on solid-state fermentation (SSF) of the filamentous fungus Aspergillus oryzae. The molecular and physiological aspects of the fungus in submerged fermentation (SmF) and SSF are compared and we observe a number of differences correlated with the different growth conditions. First, the aerial hyphae which occur only in SSFs are mainly responsible for oxygen uptake. Second, SSF is characterised by gradients in temperature, water activity and nutrient concentration, and inside the hyphae different polyols are accumulating. Third, pelleted growth in SmF and mycelial growth in SSF show different gene expression and protein secretion patterns. With this approach we aim to expand our knowledge of mechanisms of fungal growth on solid substrates and to exploit the biotechnological applications

KW - encoding gene glab

KW - fungal growth

KW - culture

KW - expression

KW - limitation

KW - oxygen

U2 - 10.1111/j.1567-1364.2002.tb00089.x

DO - 10.1111/j.1567-1364.2002.tb00089.x

M3 - Article

SN - 1567-1356

VL - 2

SP - 245

EP - 248

JO - FEMS Yeast Research

JF - FEMS Yeast Research

IS - 2

ER -

Aspergillus oryzae in solid-state and submerged fermentations. Progress report on a multi-disciplinary project

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Keywords

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