Argonaute-based nucleic acid detection system

Daniël Christianus Swarts (Inventor), Balwina Koopal (Inventor), Ana Potocnik (Inventor)

Research output: Patent

Abstract

The invention relates to a detection system for a target nucleic acid molecule that is based on a short Argonaute protein in combination with a TIR-APAZ or SIR2-APAZ protein, and the conversion of a nicotinamide adenine dinucleotide (NAD). The invention further relates to methods of detecting a specific nucleic acid molecule in a sample comprising said detection system.

Original languageEnglish
Patent numberWO2023014222
Priority date3/08/21
Publication statusPublished - 9 Feb 2023

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