Application of the Human Intestinal Tract Chip to the non-human primate gut microbiota

T.D.G. Bello Gonzalez; M.W.J. van Passel; S. Tims; S. Fuentes; W.M. de Vos; H. Smidt; C. Belzer

doi:10.3920/BM2014.0087

Application of the Human Intestinal Tract Chip to the non-human primate gut microbiota

T.D.G. Bello Gonzalez^*, M.W.J. van Passel, S. Tims, S. Fuentes, W.M. de Vos, H. Smidt, C. Belzer

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

3 Citations (Scopus)

Abstract

The human intestinal microbiota is responsible for various health-related functions, and its diversity can be readily mapped with the 16S ribosomal RNA targeting Human Intestinal Tract (HIT) Chip. Here we characterise distal gut samples from chimpanzees, gorillas and marmosets, and compare them with human gut samples. Our results indicated applicability of the HITChip platform can be extended to chimpanzee and gorilla faecal samples for analysis of microbiota composition and enterotypes, but not to the evolutionary more distant marmosets.

Original language	English
Pages (from-to)	271-276
Journal	Beneficial Microbes
Volume	6
Issue number	3
DOIs	https://doi.org/10.3920/BM2014.0087
Publication status	Published - 2015

Keywords

Enterotypes
Microbiota
Non-human primates
Phylogenetic profile

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3920/BM2014.0087

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title = "Application of the Human Intestinal Tract Chip to the non-human primate gut microbiota",

abstract = "The human intestinal microbiota is responsible for various health-related functions, and its diversity can be readily mapped with the 16S ribosomal RNA targeting Human Intestinal Tract (HIT) Chip. Here we characterise distal gut samples from chimpanzees, gorillas and marmosets, and compare them with human gut samples. Our results indicated applicability of the HITChip platform can be extended to chimpanzee and gorilla faecal samples for analysis of microbiota composition and enterotypes, but not to the evolutionary more distant marmosets.",

keywords = "Enterotypes, Microbiota, Non-human primates, Phylogenetic profile",

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T1 - Application of the Human Intestinal Tract Chip to the non-human primate gut microbiota

AU - Bello Gonzalez, T.D.G.

AU - van Passel, M.W.J.

AU - Tims, S.

AU - Fuentes, S.

AU - de Vos, W.M.

AU - Smidt, H.

AU - Belzer, C.

PY - 2015

Y1 - 2015

N2 - The human intestinal microbiota is responsible for various health-related functions, and its diversity can be readily mapped with the 16S ribosomal RNA targeting Human Intestinal Tract (HIT) Chip. Here we characterise distal gut samples from chimpanzees, gorillas and marmosets, and compare them with human gut samples. Our results indicated applicability of the HITChip platform can be extended to chimpanzee and gorilla faecal samples for analysis of microbiota composition and enterotypes, but not to the evolutionary more distant marmosets.

AB - The human intestinal microbiota is responsible for various health-related functions, and its diversity can be readily mapped with the 16S ribosomal RNA targeting Human Intestinal Tract (HIT) Chip. Here we characterise distal gut samples from chimpanzees, gorillas and marmosets, and compare them with human gut samples. Our results indicated applicability of the HITChip platform can be extended to chimpanzee and gorilla faecal samples for analysis of microbiota composition and enterotypes, but not to the evolutionary more distant marmosets.

KW - Enterotypes

KW - Microbiota

KW - Non-human primates

KW - Phylogenetic profile

U2 - 10.3920/BM2014.0087

DO - 10.3920/BM2014.0087

M3 - Article

SN - 1876-2883

VL - 6

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JO - Beneficial Microbes

JF - Beneficial Microbes

IS - 3

ER -

Application of the Human Intestinal Tract Chip to the non-human primate gut microbiota

Abstract

Keywords

UN SDGs

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