Antimicrobial resistance in commensal Escherichia coli in veal calves is associated with antimicrobial drug use

A.B. Bosman, J.A. Wagenaar, J.A. Stegeman, J.C.M. Vernooij, D.J. Mevius

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)

Abstract

The aim of this study was to determine the association between farm management factors, including antimicrobial drug usage, and resistance in commensal Escherichia coli isolates from the faeces of white veal calves. Ninety E. coli isolates from one pooled sample per farm (n = 48) were tested for their phenotypical resistance against amoxicillin, tetracycline, cefotaxime, ciprofloxacin and trimethoprim/sulfamethoxazole (TMP/SMX). Logistic regression analysis revealed the following risk factors (P <0·05); farmer wearing the same work clothes for several days [ciprofloxacin, odds ratio (OR) 2·6; tetracycline, OR 2·4], administration of trimethoprim-sulfonamide combinations (TMP/SMX, OR 3·0; amoxicillin, OR 3·1; tetracycline, OR 2·6), ¿0·3 animal daily dosage per production cycle (ADD/pc), quinolones (ciprofloxacin, OR 2·8), ¿1·3 ADD/pc, penicillins (ciprofloxacin, OR 3·3; tetracycline, OR 3·4), 20-40 ADD/pc, tetracyclines (tetracycline, OR 3·2) and >40 ADD/pc, tetracyclines (tetracycline, OR 13·1; amoxicillin, OR 6·5). In this study antimicrobial resistance in commensal E. coli was mainly associated with antimicrobial drug use.
Original languageEnglish
Pages (from-to)1893-1904
JournalEpidemiology and Infection
Volume142
Issue number9
DOIs
Publication statusPublished - 2014

Keywords

  • to-finish farms
  • antibiotic-resistance
  • fecal samples
  • exposed herd
  • risk-factors
  • pigs
  • prevalence
  • coliforms
  • bacteria
  • ontario

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