Antibiotic use in childhood alters the gut microbiota and predisposes to overweight

Katri Korpela*, W.M. de Vos

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

54 Citations (Scopus)

Abstract

A correlation between the use of antibiotics in early life and the excessive weight gain in later childhood has been shown in several large cohort studies all over the world. One hypothesis explaining this association is the pervasive impact that antibiotics may have on the intestinal microbiota, and this has been supported by recent mouse studies. Studies have shown dramatic changes in the intestinal microbiota of adults in response to oral antibiotic treatments. However, little is known about the impact of antibiotics on the intestinal microbiota of children, although antibiotics account for the majority of the medication prescribed to children in Western countries.
Original languageEnglish
Pages (from-to)296-298
JournalMicrobial Cell
Volume3
Issue number7
DOIs
Publication statusPublished - 2016

Keywords

  • Amoxicillin
  • Antibiotics
  • Asthma
  • Bile salt hydrolase
  • Child
  • Macrolide
  • Microbiota
  • Obesity

Fingerprint

Dive into the research topics of 'Antibiotic use in childhood alters the gut microbiota and predisposes to overweight'. Together they form a unique fingerprint.

Cite this