Antagonistic interactions peak at intermediate genetic similarity

S.E. Schoustra, J. Dench, R. Dali, S.D. Aaron, R.K. Kassen

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)

Abstract

Background Bacteria excrete costly toxins to defend their ecological niche. The evolution of such antagonistic interactions between individuals is expected to depend on both the social environment and the strength of resource competition. Antagonism is expected to be weak among highly similar genotypes because most individuals are immune to antagonistic agents and among dissimilar genotypes because these are unlikely to be competing for the same resources and antagonism should not yield much benefit. The strength of antagonism is therefore expected to peak at intermediate genetic distance. Results We studied the ability of laboratory strains of Pseudomonas aeruginosa to prevent growth of 55 different clinical P. aeruginosa isolates derived from cystic fibrosis patients. Genetic distance was determined using genetic fingerprints. We found that the strength of antagonism was maximal among genotypes of intermediate genetic distance and we show that genetic distance and resource use are linked. Conclusions Our results suggest that the importance of social interactions like antagonism may be modulated by the strength of resource competition
Original languageEnglish
Article number40
JournalBMC Microbiology
Volume12
DOIs
Publication statusPublished - 2012

Keywords

  • cystic-fibrosis patients
  • staphylococcus-aureus
  • bacteriocins
  • evolution
  • spite
  • virulence
  • sequence
  • ecology
  • pyocins
  • pao1

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