Abstract
The intergenic region (IR) of ambisense RNA segments from animal- and plant-infecting (-)RNA viruses functions as a bidirectional transcription terminator. The IR sequence of the Tomato spotted wilt virus (TSWV) ambisense S RNA contains stretches that are highly rich in A-residues and U-residues and is predicted to fold into a stable hairpin structure. The presence of this hairpin structure sequence in the 3' untranslated region (UTR) of TSWV mRNAs implies a possible role in translation.
Original language | English |
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Article number | e31013 |
Journal | PLoS ONE |
Volume | 7 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2012 |
Keywords
- nonstructural protein nss
- affecting transcription termination
- tail-independent translation
- cap-snatching mechanism
- escherichia-coli rna
- stem-loop structure
- cdna-based rescue
- messenger-rna
- influenza-virus
- intergenic region