Analysis of pharmaceutically relevant taxoids in wild yew trees from Sardinia

M. Ballero, M.C. Loi, E.L.M. van Rozendaal, T.A. van Beek, C. van de Haar, F. Poli, G. Appendino

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)

Abstract

Needles from a series of wild yews (Taxus baccata L.) from Sardinia were investigated for their contents of 10-deacetyl baccatin III (DAB-III, 1), paclitaxel (Taxol®) (2) and taxine (3). Despite a common geographical origin, ample variation of the taxoid profile was discovered, and several samples were surprisingly devoid of all terpenoid markers above. This finding is unprecedented within the European yew, while the general lack of taxine might rationalize the observation that most plants investigated are actively and impunently browsed by goats.
Original languageEnglish
Pages (from-to)34-39
JournalFitoterapia
Volume74
Issue number1-2
DOIs
Publication statusPublished - 2003

Keywords

  • taxus
  • needles

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