An update on organohalogen metabolites produced by basidiomycetes

J.A. Field, J.B.P.A. Wijnberg

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Abstract

Basidiomycetes are an ecologically important group of higher fungi known for their widespread capacity to produce organohalogen metabolites. To date, 100 different organohalogen metabolites (mostly chlorinated) have been identified from strains in 70 genera of Basidiomycetes. This manuscript provides an update of newly discovered chlorinated metabolites described since 1997. Additionally, the biosynthesis, physiological role, environmental fate and significance of Basidiomycete organohalogen metabolites are reviewed. Novel metabolites include chlorinated methoxybenzene azoxyformamide, pterulones (chlorinated1-benzoxepins),chlorinated anisylpropanoids, tri- and tetrachlorinated phenols. Chlorinated p-anisyl metabolites (CAM) are the most ubiquitous and ecologically significant natural organohalogens produced by higher fungi. Evidence is presented indicating their synthesis from phenylalanine via the phenylpropanoid pathway. They are estimated to be produced at a rate of 300 g ha−1 year-1 in European forests inhabited by the common occurring mushroom, Hypholoma fasciculare. Organohalogen metabolites have several purposeful physiological functions ranging from antibiotic properties, metabolites involved in lignin degradation and synthons for biosynthesis.
Original languageEnglish
Title of host publicationNatural Production of Organohalogen Compounds
Place of PublicationBerlin
Pages103-119
DOIs
Publication statusPublished - 2003

Publication series

NameThe Handbook of Environmental Chemistry
PublisherSpringer
Number3P

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