An overview of tests for animal tissues in feeds applied in response to public health concerns regarding bovine spongiform encephalopathy

G. Gizzi, L.W.D. van Raamsdonk, V. Baeten, I. Murray, G. Berben, G. Brambilla, C. von Holst

    Research output: Contribution to journalArticleAcademicpeer-review

    82 Citations (Scopus)

    Abstract

    Enforcing the ban on meat-and-bone meal in feed for farmed animals, and especially ruminants, is considered an important measure to prevent the spread of bovine spongiform encephalopathy. The authors describe current analytical methods for the detection and identification of animal tissues in feed. In addition, recently approved requirements, such as the ban of intra-species recycling (practice of feeding an animal species with proteins derived from the bodies, or parts of bodies, of the same species) are described. In principle, four different approaches are currently applied, i.e. microscopic analysis, polymerase chain reaction, immunoassay analysis and near infrared spectroscopy or microscopy. The principal performance characteristics of these methods are presented and compared, and their specific advantages and disadvantages described. Special emphasis is also placed on the impact of rendering conditions, particularly high temperatures and on the use of molecular biology techniques.
    Original languageEnglish
    Pages (from-to)311-331
    JournalRevue scientifique et technique / Office International des Epizooties
    Volume22
    Issue number1
    Publication statusPublished - 2003

    Keywords

    • species identification
    • dna-hybridization
    • bone meal
    • sensitive immunoassay
    • mitochondrial-dna
    • heat-treatment
    • pcr
    • ruminant
    • differentiation
    • validation

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