Abstract
The co-evolution of plants and plant-pathogens shaped a multi-layered defence system in plants, in which Resistance proteins (R proteins) play a significant role. A fundamental understanding of the functioning of these R proteins and their position in the broader defence system of the plant is essential. Sub-project 3 of the BIOEXPLOIT programme studies how R proteins are activated upon effector recognition and how recognition is conveyed in resistance signalling pathways, using the solanaceous R proteins Rx1 (from S. tuberosum spp. andigena; conferring extreme resistance against Potato Virus X), I-2 (from S. lycopersicon; mediating resistance to Fusarium oxysporum) and Mi-1.2 (from S. lycopersicon; conferring resistance to Meloidogyne incognita) as model systems. The results obtained in this project will serve as a model for other R proteins and will be translated to potential applications or alternative strategies for disease resistance. These include the modification of the recognition specificity of R proteins with the aim to obtain broad spectrum resistance to major pathogens in potato.
| Original language | English |
|---|---|
| Pages (from-to) | 229-235 |
| Journal | Potato Research |
| Volume | 52 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2009 |
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Slootweg, E. J., Tameling, W. I. L., Roosien, J., Lukasik, P., Joosten, M., Takken, F., Bakker, J., & Goverse, A. (2009). An Outlook on the Localisation and Structure-Function Relationships of R Proteins in Solanum. Potato Research, 52(3), 229-235. https://doi.org/10.1007/s11540-009-9130-9