An activatable, polarity dependent, dual-luminescent imaging agent with a long luminescence lifetime

M.T.M. Rood; M.E. Oikonomou; T. Buckle; M. Raspe; Y. Urano; K. Jalink; A.H. Velders; F.W.B. van Leeuwen

doi:10.1039/C4CC04015E

An activatable, polarity dependent, dual-luminescent imaging agent with a long luminescence lifetime

M.T.M. Rood, M.E. Oikonomou, T. Buckle, M. Raspe, Y. Urano, K. Jalink, A.H. Velders, F.W.B. van Leeuwen

BioNanoTechnology

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11 Citations (Scopus)

Abstract

In this proof-of-concept study, a new activatable imaging agent based on two luminophores and two different quenching mechanisms is reported. Both partial and total activation of the luminescence signal can be achieved, either in solution or in vitro. Bond cleavage makes the compound suitable for luminescence lifetime imaging.

Original language	English
Pages (from-to)	9733-9736
Journal	Chemical Communications
Volume	50
Issue number	68
DOIs	https://doi.org/10.1039/C4CC04015E
Publication status	Published - 2014

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10.1039/C4CC04015E

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title = "An activatable, polarity dependent, dual-luminescent imaging agent with a long luminescence lifetime",

abstract = "In this proof-of-concept study, a new activatable imaging agent based on two luminophores and two different quenching mechanisms is reported. Both partial and total activation of the luminescence signal can be achieved, either in solution or in vitro. Bond cleavage makes the compound suitable for luminescence lifetime imaging.",

author = "M.T.M. Rood and M.E. Oikonomou and T. Buckle and M. Raspe and Y. Urano and K. Jalink and A.H. Velders and {van Leeuwen}, F.W.B.",

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T1 - An activatable, polarity dependent, dual-luminescent imaging agent with a long luminescence lifetime

AU - Rood, M.T.M.

AU - Oikonomou, M.E.

AU - Buckle, T.

AU - Raspe, M.

AU - Urano, Y.

AU - Jalink, K.

AU - Velders, A.H.

AU - van Leeuwen, F.W.B.

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PY - 2014

Y1 - 2014

N2 - In this proof-of-concept study, a new activatable imaging agent based on two luminophores and two different quenching mechanisms is reported. Both partial and total activation of the luminescence signal can be achieved, either in solution or in vitro. Bond cleavage makes the compound suitable for luminescence lifetime imaging.

AB - In this proof-of-concept study, a new activatable imaging agent based on two luminophores and two different quenching mechanisms is reported. Both partial and total activation of the luminescence signal can be achieved, either in solution or in vitro. Bond cleavage makes the compound suitable for luminescence lifetime imaging.

U2 - 10.1039/C4CC04015E

DO - 10.1039/C4CC04015E

M3 - Article

SN - 1359-7345

VL - 50

SP - 9733

EP - 9736

JO - Chemical Communications

JF - Chemical Communications

IS - 68

ER -

An activatable, polarity dependent, dual-luminescent imaging agent with a long luminescence lifetime

Abstract

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