An activatable, polarity dependent, dual-luminescent imaging agent with a long luminescence lifetime

M.T.M. Rood, M.E. Oikonomou, T. Buckle, M. Raspe, Y. Urano, K. Jalink, A.H. Velders, F.W.B. van Leeuwen

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Abstract

In this proof-of-concept study, a new activatable imaging agent based on two luminophores and two different quenching mechanisms is reported. Both partial and total activation of the luminescence signal can be achieved, either in solution or in vitro. Bond cleavage makes the compound suitable for luminescence lifetime imaging.
LanguageEnglish
Pages9733-9736
JournalChemical Communications
Volume50
Issue number68
DOIs
Publication statusPublished - 2014

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Luminescence
Imaging techniques
Quenching
Chemical activation

Cite this

Rood, M.T.M. ; Oikonomou, M.E. ; Buckle, T. ; Raspe, M. ; Urano, Y. ; Jalink, K. ; Velders, A.H. ; van Leeuwen, F.W.B. / An activatable, polarity dependent, dual-luminescent imaging agent with a long luminescence lifetime. In: Chemical Communications. 2014 ; Vol. 50, No. 68. pp. 9733-9736.
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An activatable, polarity dependent, dual-luminescent imaging agent with a long luminescence lifetime. / Rood, M.T.M.; Oikonomou, M.E.; Buckle, T.; Raspe, M.; Urano, Y.; Jalink, K.; Velders, A.H.; van Leeuwen, F.W.B.

In: Chemical Communications, Vol. 50, No. 68, 2014, p. 9733-9736.

Research output: Contribution to journalArticleAcademicpeer-review

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T1 - An activatable, polarity dependent, dual-luminescent imaging agent with a long luminescence lifetime

AU - Rood, M.T.M.

AU - Oikonomou, M.E.

AU - Buckle, T.

AU - Raspe, M.

AU - Urano, Y.

AU - Jalink, K.

AU - Velders, A.H.

AU - van Leeuwen, F.W.B.

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AB - In this proof-of-concept study, a new activatable imaging agent based on two luminophores and two different quenching mechanisms is reported. Both partial and total activation of the luminescence signal can be achieved, either in solution or in vitro. Bond cleavage makes the compound suitable for luminescence lifetime imaging.

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DO - 10.1039/C4CC04015E

M3 - Article

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EP - 9736

JO - Chemical Communications

T2 - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

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